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Gastric Mucin

Gastric Mucin Basic information
Product Name:Gastric Mucin
Synonyms:MUCIN GASTRIC;MUCIN, GASTRIC, HOG;MUCIN TYPE I;MUCIN TYPE II;MUCIN TYPE III;MUCIN TYPE I-S;GASTRIC MUCIN PORCINE;Gastron
CAS:84082-64-4
MF:NULL
MW:0
EINECS:282-010-7
Product Categories:Mucin;Proteins and Derivatives;Structural Proteins
Mol File:Mol File
Gastric Mucin Structure
Gastric Mucin Chemical Properties
storage temp. 2-8°C
solubility 1 M NaOH: soluble20mg/mL
form partially purified powder
Safety Information
WGK Germany 3
F 10
MSDS Information
ProviderLanguage
SigmaAldrich English
Gastric Mucin Usage And Synthesis
DescriptionMucins are high-molecular-weight glycoproteins expressed throughout the gastrointestinal tract, with a key role in mucosal protection and function. In gastric cancer expression of MUC5AC and MUC1 is reduced and denovo expression of MUC2 occurs.
UsesMucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa.
General DescriptionMucins or mucus glycoproteins are the main macromolecular components of mammalian mucus. It was also used in a study to evaluate the sputum smears concentrated by cyto-centrifugation for detection of acid-fast bacilli.
Biological ActivityMucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin-17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favourable prognosis for patients.
Biochem/physiol ActionsMucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells.
Gastric Mucin Preparation Products And Raw materials
Raw materialsPepsin-->HEROIN-->gastric mucin
Aluminum acetylacetonate METHYL ISOCYANOACETATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) N-BUTYLISOCYANIDE Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) SALCOMINE 2,4-PENTANEDIONE, SILVER DERIVATIVE Tosylmethyl isocyanide COBALT(II) ACETYLACETONATE Cupric acetylacetonate Ethyl isocyanoacetate TERT-BUTYL ISOCYANIDE Ferric acetylacetonate COBALT ETHYLENE DIAMINE CHLORIDE Gastric Mucin GASTRICCANCER TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
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