ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards (2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID

(2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID

(2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID Basic information
Product Name:(2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID
Synonyms:2-(4-Ethylphenyl)propionic Acid(Ibuprofen EP Impurity N);Ibuprofen impurity 8/Ibuprofen EP Impurity N/(2RS)-2-(4-Ethylphenyl)propanoic acid;2-(4-Ethylphenyl)-propanoic acid - Racemic;IBUPROFEN IMP N;IBUPROFEN IMPURITY N;Benzeneacetic acid, 4-ethyl--alpha--methyl- (9CI);2-(4-Ethylphenyl)propionic Acid;2-(p-Ethylphenyl)propionic Acid
CAS:3585-52-2
MF:C11H14O2
MW:178.23
EINECS:
Product Categories:PHENYL
Mol File:3585-52-2.mol
(2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID Structure
(2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID Chemical Properties
Melting point 35-38℃
Boiling point 135 °C(Press: 3.5 Torr)
density 1.067
storage temp. Refrigerator, under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly, Sonicated)
pka4.43±0.10(Predicted)
form Solid
color Colourless to Off-White Oil
BRN 204763
Safety Information
MSDS Information
(2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID Usage And Synthesis
Usesp-Ethylhydratropic Acid is a phenylacetic acid with potential antiinflammatory activities. p-Ethylhydratropic Acid is an impurity of Ibuprofen (I140000).
Usesp-Ethylhydratropic Acid (Ibuprofen EP Impurity N) is a phenylacetic acid with potential antiinflammatory activities. p-Ethylhydratropic Acid is an impurity of Ibuprofen (I140000).
Synthesis Reference(s)Tetrahedron Letters, 31, p. 7495, 1990 DOI: 10.1016/S0040-4039(00)88526-3
(2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID Preparation Products And Raw materials
Raw materials1-Propanone, 2-chloro-1-(4-ethylphenyl)- (9CI)-->4'-Ethylpropiophenone
(S)-(+)-Ibuprofen (R)-(-)-IBUPROFEN Ibuprofen IBUPROFEN SODIUM SALT METHYL 4-(4-CHLOROPHENYL)-2-(4-ETHYLPHENYL)-4-OXOBUTANOATE Carebastine Suprofen IBUPROFEN, RS, [CARBOXYL-14C] NOGALAMYCIN hexaprofen IBUPROFEN, RS, [3H(G)] 4-(4-CHLOROPHENYL)-2-(4-ETHYLPHENYL)-4-OXOBUTANOIC ACID CLIDANAC METHYL 4-(4-CHLOROPHENYL)-2-(4-ISOPROPYLPHENYL)-4-OXOBUTANOATE IBUPROFEN, R(-) [CARBOXYL-14C] IBUPROFEN, S(+), [CARBOXYL-14C] 4-(4-CHLOROPHENYL)-2-(4-ISOPROPYLPHENYL)-4-OXOBUTANOIC ACID Loxoprofen
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