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| | (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE Basic information |
| Product Name: | (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE | | Synonyms: | (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE;(1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMI DE, 1.0M SOLUTION IN THF;(1,3-dioxolan-2-ylmethyl)magnesium bromide solution;(1,3-Dioxolan-2-ylMethyl)MagnesiuM broMide, 0.5M solution in THF, AcroSeal;Bromo(1,3-dioxolan-2-ylmethyl)magnesium;MagnesiuM,broMo(1,3-dioxolan-2-ylMethyl)-;(1,3-Dioxolan-2-ylMethyl)MagnesiuM broMide solution 0.5 M in THF;1,3-Dioxolan-2-ylmethylmagnesium bromide, 0.50 M in THF | | CAS: | 180675-22-3 | | MF: | C4H7BrMgO2 | | MW: | 191.31 | | EINECS: | | | Product Categories: | Alkyl;Grignard Reagents;Organometallic Reagents | | Mol File: | 180675-22-3.mol |  |
| | (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE Chemical Properties |
| Boiling point | 65-67 °C | | density | 0.938 g/mL at 25 °C | | Fp | −4 °F | | form | Powder | | color | White to off-white to pale brown |
| | (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE Usage And Synthesis |
| Uses | (1,3-Dioxolan-2-ylmethyl)magnesium bromide is a Grignard reagent that can be used to prepare:
- 3-[11C]-Propionaldehyde, a key intermediate for the synthesis of radiolabeled compound [11C]SN-38, wherein SN-38 is 7-ethyl-10-hydroxy camptothecin.
- 1-[(S)-2,2-Dimethyl-(1,3)-dioxolan-4-yl]-4-(1,3-dioxolan2-yl)-2-ol by reacting with D-glyceraldehyde, which is further used to synthesize unsaturated nucleosides.
- A bicyclo carboxylate intermediate, which is employed in the total synthesis of spirovibsanin A.
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| | (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE Preparation Products And Raw materials |
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