NILOTINIB IMPURITY 17

NILOTINIB IMPURITY 17 Basic information
Product Name:NILOTINIB IMPURITY 17
Synonyms:NILOTINIB IMPURITY 17;4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide;Nilotinib Amide Impurity;4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide;Benzamide, 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-
CAS:851137-91-2
MF:C17H15N5O
MW:305.33
EINECS:
Product Categories:
Mol File:851137-91-2.mol
NILOTINIB IMPURITY 17 Structure
NILOTINIB IMPURITY 17 Chemical Properties
Melting point 201-203°C
Boiling point 554.0±60.0 °C(Predicted)
density 1.297±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka16.17±0.50(Predicted)
color White to Beige
Safety Information
MSDS Information
NILOTINIB IMPURITY 17 Usage And Synthesis
Uses4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide is an impurity of Nilotinib (N465300), a possible agent in the treatment of chronic myelogenous leukemia.
NILOTINIB IMPURITY 17 Preparation Products And Raw materials
3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamide Nilotinib impurity 3 Nilotinib Impurity 28 Nilotinib Impurity 20 Nilotinib Impurity 1 Nilotinib genotoxic impurity 3 Nilotinib Impurity 7 Nilotinib N-Oxide Nilotinib Impurity 10 Benzenamine, 3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)- 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile 1H-IMidazole, 4-Methyl-1-[3-nitro-5-(trifluoroMethyl)phenyl]- 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate 3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)benzenaMine 4-Methyl-N-(3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)phenyl)-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzaMide NILOTINIB IMPURITY 11 Nilotinib Impurity 27

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