MES sodium salt

MES sodium salt Basic information
Product Name:MES sodium salt
Synonyms:Natrium-4-morpholin-1-ylethylsulfonat;2-(N-Morpholino)ethanesulphonic acid sodium salt;4-Morpholine-1-ethanesulfonic acid sodium salt;MES sodium salt,99%;2-(N-Morpholino)ethanesulfonic acid sodium salt, 4-Morpholineethanesulfonic acid sodium salt;4-Morpholineethanesulfonic acid, sodium salt (1:1);Einecs 275-203-2;MES sodium salt,2-(N-Morpholino)ethanesulfonic acid sodium salt, 4-Morpholineethanesulfonic acid sodium salt
CAS:71119-23-8
MF:C6H14NNaO4S
MW:219.23
EINECS:275-203-2
Product Categories:Pharmaceutical Raw Materials
Mol File:71119-23-8.mol
MES sodium salt Structure
MES sodium salt Chemical Properties
Melting point >250?C (dec.)
density 1.507[at 20℃]
vapor pressure 0Pa at 25℃
storage temp. room temp
solubility H2O: 0.5 g/mL, clear, colorless
form Powder
color White
PH Range5.5 - 6.7
Water Solubility 335.3g/L at 20℃
BRN 3765682
InChIInChI=1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1
InChIKeyIRHWMYKYLWNHTL-UHFFFAOYSA-M
SMILESS([O-])(=O)(=O)CCN1CCOCC1.[Na+]
LogP-2.36 at 20℃
CAS DataBase Reference71119-23-8(CAS DataBase Reference)
EPA Substance Registry System4-Morpholineethanesulfonic acid, sodium salt (71119-23-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 1
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
MES sodium salt Usage And Synthesis
Chemical PropertiesWhite powder
UsesMES Sodium is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

MES Sodium is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.
UsesMES sodium salt is a buffering agent used in biological and biochemical research including plant cell culture. It has been used:
To achieve the required density and stretching of DNA fibers during melting of agarose plugs containing genomic DNA.
To equilibrate the Balch homogenizer chamber and to prevent sample hydrolysis before sample homogenization.
DefinitionChEBI: Sodium 2-(N-morpholino)ethanesulfonate is the organic sodium salt that is the sodium salt of 2-(N-morpholino)ethanesulfonic acid. It contains a 2-(N-morpholino)ethanesulfonate.
General DescriptionMES is one of the so-called "Good" buffers developed for biological applications. This product is BioPerformance certified (suitable for electrophoresis, tissue culture, and molecular biology applications. A buffer using MES free acid can be prepared by titrating the free acid with sodium hydroxide to the desired pH (pKa=±1). Alternatively, volumes of equimolar solutions of MES free acid and MES sodium can be mixed to attain the desired pH. Standard mixing tables using stock solutions to prepare a buffer of a given pH have been published.
Flammability and ExplosibilityNotclassified
MES sodium salt Preparation Products And Raw materials
Raw materialsMorpholine-->Sodium isethionate
Sodium benzoate Moroxydine hydrochloride 4-Morpholineethanesulfonic acid MORPHOLINEFATTYACIDSALT sodium Moroxydine Ethanesulfonic acid Sodium formate Sodium citrate MES monohydrate Sodium bicarbonate { MES SODIUM SALT NH 2-(N-Morpholino)ethanesulfonic acid hemisodium salt Tridemorph MES, Sodium Salt, ULTROL Grade 2-Diethylaminoethanethiol 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Dimethomorph

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