4-Chlorobenzenesulfonyl chloride

4-Chlorobenzenesulfonyl chloride Basic information

Product Name:	4-Chlorobenzenesulfonyl chloride
Synonyms:	4-chloro-benzenesulfonicacichloride;4-chloro-benzenesulfonylchlorid;Benzenesulfonyl chloride, 4-chloro-;Benzenesulfonyl chloride, p-chloro-;Benzenesulfonylchloride,4-chloro-;Chlorid kyseliny p-chlorbensulfonove;4-Chorobenzenesulphonyl chloride;chloridkyselinyp-chlorbensulfonove
CAS:	98-60-2
MF:	C6H4Cl2O2S
MW:	211.07
EINECS:	202-685-3
Product Categories:	Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;bc0001
Mol File:	98-60-2.mol

4-Chlorobenzenesulfonyl chloride Chemical Properties

Melting point	50-52 °C (lit.)
Boiling point	141 °C/15 mmHg (lit.)
density	1.5075 (estimate)
Fp	226 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	soluble in Toluene
form	Liquid
color	Clear
Water Solubility	INSOLUBLE
Sensitive	Moisture Sensitive
BRN	511583
CAS DataBase Reference	98-60-2(CAS DataBase Reference)
NIST Chemistry Reference	4-Chlorobenzenesulfonyl chloride(98-60-2)
EPA Substance Registry System	Benzenesulfonyl chloride, 4-chloro- (98-60-2)

Safety Information

MSDS Information

Provider	Language
4-Chlorobenzenesulfonyl chloride	English
SigmaAldrich	English
ACROS	English
ALFA	English

4-Chlorobenzenesulfonyl chloride Usage And Synthesis

Chemical Properties	white to light yellow crystals, powder or flakes
Uses	4-Chlorobenzenesulfonyl chloride was used in the synthesis of precursors for the 3,4-pyridyne generation.
Synthesis Reference(s)	The Journal of Organic Chemistry, 7, p. 15, 1942 DOI: 10.1021/jo01195a003
Purification Methods	Crystallise it from ether in powdered Dry-Ice, after the solution has been washed with 10% NaOH until colourless and dried (Na2SO4). Distil it in vacuo and store it in the absence of H2O. [Beilstein 11 IV 114.]

4-Chlorobenzenesulfonyl chloride Preparation Products And Raw materials

Raw materials	Chlorosulfonic acid-->Chlorobenzene-->Sulfanilic acid-->4-CHLOROBENZENESULFONIC ACID SODIUM SALT-->Benzenesulfonothioic acid, 4-chloro-, S-(4-chlorophenyl) ester-->Carbamothioic acid,N-methyl-, S-(4-chlorophenyl) ester-->S-4-Chlorophenylthioacetate-->4,4'-DICHLORODIPHENYL DISULFIDE-->4-Chlorobenzenesulfonic acid-->4-Chlorothiophenol
Preparation Products	CARBOPHENOTHION-->4-Chlorobenzenesulfonamide-->Daltroban-->OVEX-->Sulfenone-->1,2-Bis(4-chlorophenyl)ethane-->4-CHLOROPHENYLSULFONYLACETONITRILE-->3-BROMO-4'-CHLOROBENZOPHENONE-->Avagacestat (BMS-708163)-->4-Chloro-3-nitrobenzenesulfonyl chloride-->2-[(4-Chlorophenylsulphonyl)amino]benzyl alcohol

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