|
| | (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Basic information |
| Product Name: | (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID | | Synonyms: | (1S,3R)-(+)-3-Aminocyclopentane-1-carboxylic acid, N-BOC protected;(+)-(1S,3R)-N-Boc-3-aMinocyclopentanecarboxylic acidacid;(1S,3R)-3-((tert-Butoxycarbonyl)aMino)cyclopentanecarboxylic acid;Cis(1S,3R)-3-((tert-butoxycarbonyl)aMino) cyclopentanecarboxylic acid;(1S,3R)-(+)-3-(Boc-amino)cyclopentanecarboxylic acid >=96.0% (HPLC);(1S,3R)-3-(tert-Butoxycarbonylamino)cyclopentanecarboxylic Acid;Cyclopentanecarboxylicacid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (1S,3R)-;(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID | | CAS: | 261165-05-3 | | MF: | C11H19NO4 | | MW: | 229.27 | | EINECS: | | | Product Categories: | Unnatural Amino Acid Derivatives;Unusual amino acids;API intermediates;Beta-Amino Acids;Peptide Synthesis | | Mol File: | 261165-05-3.mol |  |
| | (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Chemical Properties |
| Melting point | 35-49 °C | | Boiling point | 371.18°C (rough estimate) | | density | 1.1482 (rough estimate) | | refractive index | 1.4490 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | slightly sol. in Methanol | | pka | 4.62±0.40(Predicted) | | form | Powder or Chunks | | color | White | | optical activity | [α]/D +16.0±1°, c = 1% in methanol |
| Hazard Codes | Xi | | Safety Statements | 22-24/25 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29223900 |
| | (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Usage And Synthesis |
| Chemical Properties | white powder or chunks | | Uses | (-)-(1R,3S)-N-Boc-1-Aminocyclopentane-3-carboxylic Acid is a reagent used in the synthesis of 3-substituted aminocyclopentanes as potent NR2B subtype-sellective NMDA antagonists in the treatment of neuropathic pain and Parkinson’s. |
| | (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Preparation Products And Raw materials |
| Raw materials | 2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 3-oxo-, 1,1-dimethylethyl ester, (1R,4S)--->(1S,4R)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate-->2-Azabicyclo[2.2.1]heptan-3-one-->(1R,4S)-4-Aminocyclopent-2-enecarboxylic acid-->(1S,3R)-Methyl 3-[(tert-butoxycarbonyl)-amino]cyclopentanecarboxylate-->(1S,3R)-3-Aminocyclopentanecarboxylic acid-->(+)-(1R,4S)-N-BOC-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID-->Di-tert-butyl dicarbonate-->2-Azabicyclo[2.2.1]hept-5-en-3-one-->Acetic anhydride | | Preparation Products | (-)-(1R,3S)-N-Boc-3-Aminocyclopentanecarboxylic acid-->methyl (1R,3R)-3-{[(tert-butoxy)carbonyl]amino}cyclopentane-1-carboxylate |
|
