ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Fluoropyrimidine 4-Ethyl-5-fluoro-6-hydroxypyrimidine

4-Ethyl-5-fluoro-6-hydroxypyrimidine

4-Ethyl-5-fluoro-6-hydroxypyrimidine Basic information
Product Name:4-Ethyl-5-fluoro-6-hydroxypyrimidine
Synonyms:6-Ethyl-5-fluoropyrimidin-4(3H)-one;6-ETHYL-5-FLUORO-PYRIMIDIN-4-OL;4-ETHYL-5-FLUORO-6-HYDROXYPYRIMIDINE;6-Ethyl-5-fluoro-4(1H)-pyrimidinone;6-Ethyl-5-fluoropyrimidin-4-one;4(1H)-Pyrimidinone, 6-ethyl-5-fluoro- (9CI);4-hydroxy-5-fluoro-6-ethylpyrimidine;4-Ethyl-5 fluoro-6-hydroxypirimidine
CAS:137234-87-8
MF:C6H7FN2O
MW:142.13
EINECS:422-460-5
Product Categories:Fluorine series;Aromatics;APIs & Intermediate;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;PYRIMIDINE
Mol File:137234-87-8.mol
4-Ethyl-5-fluoro-6-hydroxypyrimidine Structure
4-Ethyl-5-fluoro-6-hydroxypyrimidine Chemical Properties
Melting point 114-116oC
Boiling point 180.7±50.0 °C(Predicted)
density 1.30±0.1 g/cm3(Predicted)
vapor pressure 0.001Pa at 25℃
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka7.52±0.50(Predicted)
color White to Pale Brown
Water Solubility 94.9g/L at 20℃
LogP0.19 at 20℃
CAS DataBase Reference137234-87-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,N,Xn
Risk Statements 22-50/53
Safety Statements 60-61
HazardClass IRRITANT
HS Code 2933599590
MSDS Information
4-Ethyl-5-fluoro-6-hydroxypyrimidine Usage And Synthesis
Chemical PropertiesWhite powder
Uses4-Ethyl-5-fluoro-6-hydroxypyrimidine is a pyrimidine derivative used in the preparation of bio-active compounds such as broad-spectrum triazole antifungal agents.
Flammability and ExplosibilityNotclassified
4-Ethyl-5-fluoro-6-hydroxypyrimidine Preparation Products And Raw materials
Preparation Products4-Chloro-6-ethyl-5-fluoropyrimidine-->6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine
6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine Voriconazole Impurity 53 Voriconazole (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride 1,2,4-Triazole 2-Chloro-2',4'-difluoroacetophenone Pyrimidine, 4-bromo-6-(1-bromoethyl)-5-fluoro- Pyrimidine, 4,4'-(1,2-dimethyl-1,2-ethanediyl)bis[2,6-dichloro-5-fluoro- (9CI) (2R,3S/2S,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol 1-Butanesulfonic acid, 4-hydroxy-, methyl ester Ethanone, 1-(3,5-difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)- Voriconazole Impurity 16 4-Ethyl-5-fluoropyrimidine 5-Fluoropyrimidine 2-CHLORO-6-ETHYL-5-FLUORO-4-HYDROXYPYRIMIDINE Pyrimidine 4-Hydroxy-5-fluorpyrimidine 4-Ethyl-5-fluoro-6-hydroxypyrimidine
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