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| | 2,5-Dibromobenzoic acid Basic information |
| Product Name: | 2,5-Dibromobenzoic acid | | Synonyms: | 2,5-dibromo-benzoicaci;Benzoic acid, 2,5-dibromo-;2,5-DIBROMOBENZOIC ACID;2,5-Dibromobenzoicacid,95%;5-DibroMobenzoic acid;2,5-DibroMobenyoic, Acid;Dapagliflozin Impurity P;2,5- twobroMo benzoic acid | | CAS: | 610-71-9 | | MF: | C7H4Br2O2 | | MW: | 279.91 | | EINECS: | 210-234-7 | | Product Categories: | Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Benzoic acid;Organic acids;Acids & Esters;Bromine Compounds;C7;Carbonyl Compounds;Carboxylic Acids;bc0001 | | Mol File: | 610-71-9.mol |  |
| | 2,5-Dibromobenzoic acid Chemical Properties |
| Melting point | 156-159 °C(lit.) | | Boiling point | 344.6±32.0 °C(Predicted) | | density | 1.9661 (rough estimate) | | refractive index | 1.4970 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | form | powder to crystal | | pka | 2.46±0.10(Predicted) | | color | White to Yellow to Orange | | BRN | 1868193 | | CAS DataBase Reference | 610-71-9(CAS DataBase Reference) | | NIST Chemistry Reference | 2,5-Dibromobenzoic acid(610-71-9) |
| Hazard Codes | Xi,C | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | DG6290000 | | HS Code | 29163990 |
| | 2,5-Dibromobenzoic acid Usage And Synthesis |
| Chemical Properties | off-white powder | | Uses | 2,5-Dibromobenzoic Acid is an intermediate used to prepare benzo[c]chromenone and benzo[c]chromene derivatives as estrogen β-receptor-selective agonists in comparison with effusol and estradiol. It is also used in the synthesis of aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity. | | Purification Methods | Crystallise the acid from water or EtOH. [Beilstein 9 H 358, 9 I 147, 9 II 237, 9 III 1428, 9 IV 1027.] |
| | 2,5-Dibromobenzoic acid Preparation Products And Raw materials |
| Raw materials | Anthranilic acid | | Preparation Products | 6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE-->5-BROMO-HOMOPHTHALIC ACID-->S)-1-(sec-butyl)-N-((4,6-diMethyl-2-oxo-1,2-dihydropyridin-3-yl)Methyl)-3-Methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxaMide-->1,4-DIBROMO-2-(CHLOROMETHYL)BENZENE-->2-(2,5-DibroMophenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane |
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