2-METHOXY-3-PYRIDINECARBOXALDEHYDE

2-METHOXY-3-PYRIDINECARBOXALDEHYDE Basic information

Product Name:	2-METHOXY-3-PYRIDINECARBOXALDEHYDE
Synonyms:	2-METHOXYNICOTINALDEHYDE;2-METHOXY-PYRIDINE-3-CARBALDEHYDE;2-METHOXY-3-PYRIDINECARBOXALDEHYDE;3-Pyridinecarboxaldehyde, 2-methoxy- (9CI);2-Methoxy-3-pyridinecarboxaldenhyde;2-Methoxy-3-pyridinecaarboxaldehyde;2-METHYOXYNICOTINALDEHYDE;2-Methoxypyridine-3-carboxaldehyde
CAS:	71255-09-9
MF:	C7H7NO2
MW:	137.14
EINECS:
Product Categories:	Heterocycle-Pyridine series;ALDEHYDE;C7 and C8;Heterocyclic Building Blocks;Pyridines
Mol File:	71255-09-9.mol

2-METHOXY-3-PYRIDINECARBOXALDEHYDE Chemical Properties

Boiling point	200-201 °C (lit.)
density	1.161 g/mL at 25 °C (lit.)
refractive index	n20/D 1.5500(lit.)
Fp	205 °F
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
form	Liquid or Low Melting Solid
pka	1.60±0.10(Predicted)
color	Colorless to yellow
Sensitive	Air Sensitive
CAS DataBase Reference	71255-09-9(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

2-METHOXY-3-PYRIDINECARBOXALDEHYDE Usage And Synthesis

Chemical Properties	Colorless to yellow liquid
Uses	2-Methoxy-3-pyridinecarboxaldehyde may be used to synthesize the following: ethyl 5-amino-4-(2-methoxy-3-pyridyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrano[2,3-b]quinoline-3-carboxylate, a potent AChE inhibitor N-hydroxy-2-pyridinone-based arylsulfone containing a Zn-binding group (ZBG) as MMP-2/-9 inhibitor
Synthesis Reference(s)	Tetrahedron Letters, 29, p. 773, 1988 DOI: 10.1016/S0040-4039(00)80206-3

2-METHOXY-3-PYRIDINECARBOXALDEHYDE Preparation Products And Raw materials

Raw materials	Ethyl acetate-->Diethyl ether-->Tetrahydrofuran-->Acetic acid-->Sodium-->N,N-Dimethylformamide-->Magnesium sulfate-->Sodium chloride-->Sodium bicarbonate-->Hexane-->Nitrogen-->tert-Butyllithium-->2-Methoxypyridine-->2,4,6-Trimethybromombenzene
Preparation Products	2-METHOXY-3-CHLOROMETHYL PYRIDINE-->3-(2-METHOXYPYRIDIN-3-YL)ACRYLIC ACID

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