3-COUMARANONE

3-COUMARANONE Basic information
Product Name:3-COUMARANONE
Synonyms:3-Oxocoumaran;3-Coumaranonebenzofuran-3(2H)-one;Benzo[b]furan-3(2H)-one;1-Benzofuran-3(2H)-one;1-Benzofuran-3(2H)-one, Coumaran-3-one;2,3-dihydro-1-benzofuran-2-one;1-Benzofuran-3(2H)-one, Coumaran-3-one, 2,3-Dihydro-3-oxo-1-benzofuran;Benzofuran-3(2H)-one >=98.0% (HPLC)
CAS:7169-34-8
MF:C8H6O2
MW:134.13
EINECS:640-279-1
Product Categories:Benzofurans;Building Blocks;pharmacetical;Fused Ring Systems;Chemical Synthesis;Heterocyclic Building Blocks;Furan&Benzofuran
Mol File:7169-34-8.mol
3-COUMARANONE Structure
3-COUMARANONE Chemical Properties
Melting point 101-103 °C
Boiling point 207.23°C (rough estimate)
density 1.1603 (rough estimate)
refractive index 1.4800 (estimate)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility Chloroform (Slightly), DMSO (Slightly)
form Solid
color Yellow to Dark Yellow
Water Solubility Slightly miscible with water.
Sensitive Light Sensitive
BRN 115296
CAS DataBase Reference7169-34-8(CAS DataBase Reference)
NIST Chemistry Reference3(2H)-benzofuranone(7169-34-8)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 22-24/25-36/37/39-26-36
WGK Germany 3
4.5-9
Hazard Note Irritant
HS Code 29329990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
3-COUMARANONE Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powde
Uses3-Coumaranone is used in the aurones, [2-benzylidenebenzofuran-3(2H)-ones] by reacting with appropriate aldehyde. It is involved in the condensation reaction with aldehydes in the presence of morpholine acetate to prepare substituted 2-(arylidene)benzofuran-3(ZH)-ones. In Horner-Wadsworth-Emmons reaction, it reacts with diethyl? cyanomethyl?phosphonate to give 3-(cyanomethyl)benzofurans, which is an intermediate in the synthesis of antihyperglycemic agents.
General DescriptionBenzofuran-3(2H)-one undergoes condensation with aldehydes in the presence of morpholine acetate to yield substituted 2-(arylidene)benzofuran-3(ZH)-ones. It undergoes acid- or base-catalyzed condensation with an appropriate aldehyde to yield aurones [2-benzylidenebenzofuran-3(2H)-ones].
AUREUSIDIN-4-METHYL ETHER 6,4'-DIHYDROXYAURONE AUREUSIDIN(RG) (+)-Griseofulvin MARITIMEIN 5-CHLORO-BENZOFURAN-3-ONE 3-Ketocarbofuranphenol 4-O-(Carboxymethyl)rifamycin 6-HYDROXY-3-COUMARANONE 3',4',6,7-TETRAHYDROXYAURONE SULFURETIN CARBOFURAN-3-KETO Rifamycin Sodium Rifampicin 7-METHOXY-3(2H)-BENZOFURANONE LABOTEST-BB LT00244818 3-COUMARANONE 3-OXO-2,3-DIHYDROBENZO[B]FURAN-6-YL 2,3,3-TRICHLOROACRYLATE

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