Linagliptin Impurity H

Linagliptin Impurity H Basic information
Product Name:Linagliptin Impurity H
Synonyms:Linagliptin Impurity H;1-((4-methylquinazolin-2-yl)methyl)piperidin-3-amine;Linagliptin impurity 12/7-(2-Butyn-1-yl)-8-(dimethylamino)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione;Linagliptin Imp.K;1H-Purine-2,6-dione, 7-(2-butyn-1-yl)-8-(dimethylamino)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-;Linagliptin H;7-(but-2-yn-1-yl)-8-(dimethylamino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione;7-(But-2-yn-1-yl)-8-(dimethylamino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione (Linagliptin Impurity)
CAS:1646355-34-1
MF:C22H23N7O2
MW:417.46
EINECS:
Product Categories:
Mol File:1646355-34-1.mol
Linagliptin Impurity H Structure
Linagliptin Impurity H Chemical Properties
Boiling point 583.0±60.0 °C(Predicted)
density 1.30±0.1 g/cm3(Predicted)
pka2.47±0.50(Predicted)
Safety Information
MSDS Information
Linagliptin Impurity H Usage And Synthesis
Uses7-(But-2-yn-1-yl)-8-(dimethylamino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione is an impurity of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.
Linagliptin Impurity H Preparation Products And Raw materials
Linagliptin iMpurity Linagliptin Impurity F 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione Linagliptin MethyldiMer Linagliptin iMpurity E Linagliptin Impurity C Tert-butyl((3s)-1-(7-(but-2-yn-1-yl)-3-Methyl-1-((4-Methylquinazolin-2-yl)Methyl)-2,6-dioxo-2,3,4,5,6,7-hexahydro-1h-purin-8-yl)piperidin-3-yl)carbaMate Linagliptin Dimer Impurity 6 Linagliptin N-Acetyl Impurity Linagliptin 8-Bromo-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione Linagliptin iMpurity G Linagliptin Impurity K Linagliptin Impurity D Linagliptin Impurity 10 Linagliptin Impurity JX

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