p-Aminobenzamide

p-Aminobenzamide Basic information

Product Name:	p-Aminobenzamide
Synonyms:	(4-Aminophenyl)carboxamide;4-amino-benzamid;4-Aminobenzenecarboxamide;4-Carbamoylaniline;aminobenzamide;Benzamide, p-amino-;Benzamide,4-amino-;Benzamide,p-amino-
CAS:	2835-68-9
MF:	C7H8N2O
MW:	136.15
EINECS:	220-612-3
Product Categories:	Azaindoles ,Indolines ,Indoles;Building Blocks;Amides;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;AMIDE;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carbonyl Compounds;Organic Building Blocks;2835-68-9
Mol File:	2835-68-9.mol

p-Aminobenzamide Chemical Properties

Melting point	181-183 °C(lit.)
Boiling point	250.42°C (rough estimate)
density	1.1778 (rough estimate)
vapor pressure	0.001-0.001Pa at 25℃
refractive index	1.5769 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	16.83±0.50(Predicted)
form	Crystalline Powder
color	Off-white to beige
Water Solubility	Slightly soluble in water.
BRN	2079485
LogP	-0.38 at 23℃ and pH7
CAS DataBase Reference	2835-68-9(CAS DataBase Reference)
NIST Chemistry Reference	Benzamide, 4-amino-(2835-68-9)
EPA Substance Registry System	Benzamide, 4-amino- (2835-68-9)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	20/22-36/38-36/37/38
Safety Statements	38-37/39-26-36
WGK Germany	1
TSCA	Yes
HazardClass	IRRITANT
HS Code	29242990

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

p-Aminobenzamide Usage And Synthesis

Chemical Properties	off-white to beige crystalline powder
Uses	4-Aminobenzamide was used as a poly(ADP-ribose)polymerase (PADPRP) inhhibitor to study the death of target cells by cytotoxic effector cells using the nuclear enzyme poly(ADP-ribose)polymerase (PADPRP).
Definition	ChEBI: 4-Aminobenzamide is a member of benzamides.
Synthesis Reference(s)	Synthetic Communications, 25, p. 4025, 1995 DOI: 10.1080/00397919508011478

p-Aminobenzamide Preparation Products And Raw materials

Raw materials	Ammonium hydroxide-->Iron-->p-Nitrobenzoic acid-->4-Nitrobenzoyl chloride-->Benzamide, 4,4'-azobis- (8CI,9CI)-->Benzamide, 4-azido--->Benzoyl chloride, 4-amino- (9CI)-->4-BROMOBENZAMIDE-->Ethyl p-nitrobenzoate-->4-Aminoacetophenone-->4-Nitrobenzonitrile-->4-Aminobenzonitrile
Preparation Products	Leather Coating Red GL-->Pigment Permanent Red F5RK-->4-Aminobenzylamine-->4-AMINOBENZANILIDE-->4-isothiocyanatobenzamide-->4-AMINO-N-(3,5-DIMETHYLPHENYL)BENZAMIDE

Chlorantraniliprole 4-NITROBENZHYDRAZIDE 4-AMINO-1,8-NAPHTHALIMIDE P-NITROBENZOYL-L-GLUTAMIC ACID 2-AMINOBENZAMIDE 4-AMINO-3,5-DINITROBENZAMIDE 4-Nitrophthalimide D(-)-AMETHOPTERIN HYDRATE, 98 Benzamide N-(4-AMINOBENZOYL)-L-GLUTAMIC ACID DIETHYL ESTER Calcium folinate 4-NITROHIPPURIC ACID LUCIFER YELLOW CH DILITHIUM SALT p-Aminobenzamide N-ACETYLPROCAINAMIDE 4-Aminobenzohydrazide N-(4-NITROBENZOYL)-L-GLUTAMIC ACID DIETHYL ESTER 4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE

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