2,2'-(4,4'-(3,3'-(isopropylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy)bis(4,1-phenylene))diacetaMide

2,2'-(4,4'-(3,3'-(isopropylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy)bis(4,1-phenylene))diacetaMide Basic information
Product Name:2,2'-(4,4'-(3,3'-(isopropylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy)bis(4,1-phenylene))diacetaMide
Synonyms:2,2'-(4,4'-(3,3'-(isopropylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy)bis(4,1-phenylene))diacetaMide;Atenolol IMpurity –F(EP);Atenolol EP IMpurity F;4,4'-[[(1-Methylethyl)imino]bis[(2-hydroxy-3,1-propanediyl)oxy]]bis-benzeneacetamide (Atenolol Impurity F);Atenolol Related CoMpound D;4,4'-[[(1-Methylethyl)imino]bis[(2-hydroxy-3,1-propanediyl)oxy]]bisbenzeneacetamide;Atenolol Related Compound D (20 mg) (N-Isopropyl-N,N-bis{3-[4-(2-amino-2-oxoethyl)phenoxy]-2-hydroxyprop-1-yl}amine);2,2'-((((Isopropylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy))bis(4,1-phenylene))diaceta
CAS:87619-83-8
MF:C25H35N3O6
MW:473.56
EINECS:
Product Categories:
Mol File:87619-83-8.mol
2,2'-(4,4'-(3,3'-(isopropylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy)bis(4,1-phenylene))diacetaMide Structure
2,2'-(4,4'-(3,3'-(isopropylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy)bis(4,1-phenylene))diacetaMide Chemical Properties
Melting point 160-162oC
Boiling point 780.4±60.0 °C(Predicted)
density 1.231±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Methanol (Slightly, Sonicated)
pka13.51±0.20(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
2,2'-(4,4'-(3,3'-(isopropylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy)bis(4,1-phenylene))diacetaMide Usage And Synthesis
Uses4,4''-[[(1-methylethyl)imino]bis[(2-hydroxy-3,1-propanediyl)oxy]]bis-benzeneacetamide (Atenolol USP Related Compound D; Atenolol EP Impurity F) is an impurity of Atenolol (A790075), a cardioselective β-adrenergic blocker.
Uses4,4'-[[(1-methylethyl)imino]bis[(2-hydroxy-3,1-propanediyl)oxy]]bis-benzeneacetamide is an impurity of Atenolol (A790075), a cardioselective β-adrenergic blocker.
2,2'-(4,4'-(3,3'-(isopropylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy)bis(4,1-phenylene))diacetaMide Preparation Products And Raw materials
Metoprolol Acid IMp. H (EP): 2-[4-[(2RS)-2-Hydroxy-3-[(1-Methylethyl)aMino]propoxy]phenyl]acetonitrile 2-[4-(2,3-EPOXYPROPOXY)PHENYL]ACETAMIDE 2-[4-(2,3-DIHYDROXYPROPOXY)PHENYL]ACETAMIDE 2-[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]ACETAMIDE 4-Hydroxyphenylacetamide 4,4'-(2-HYDROXY-1,3-PROPANDIYLDIOXY)BIS(2-PHENYLACETAMIDE) ATENOLOL-D7 C-Desmethyl Atenolol Atenolol 4-(3-Amino-2-hydroxypropoxy)phenylacetamide 4-Hydroxyphenylacetic acid [[p-(2-methoxyethyl)phenoxy]methyl]oxirane Atenolol EP Impurity G Sodium Salt 2-[4-[(2RS)-2-HYDROXY-3[(1-METHYLETHYL)AMINO]PROPOXY]PHENYL]ACETONITRILE

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