2,5-Di-tert-butylhydroquinone

2,5-Di-tert-butylhydroquinone Basic information

Product Name:	2,5-Di-tert-butylhydroquinone
Synonyms:	DI-TERT-BUTYL HYDROQUINONE(2,5-);DI-T-BUTYLHYDROQUINONE;2,5-Di-tert-butylquinol;Di-Tertiary Butylhydroquinone;DTBHQ (DI-TERTIARY BUTYL;4-Benzenediol,2,5-bis(1,1-dimethylethyl)-1;antagedbh;dibug
CAS:	88-58-4
MF:	C14H22O2
MW:	222.32
EINECS:	201-841-8
Product Categories:	Signalling;Organic Building Blocks;Oxygen Compounds;Polyols;Anthraquinones, Hydroquinones and Quinones;Calcium signaling;Industrial/Fine Chemicals
Mol File:	88-58-4.mol

2,5-Di-tert-butylhydroquinone Chemical Properties

Melting point	216-218 °C(lit.)
Boiling point	321°C
density	1,07 g/cm³
refractive index	1.4576 (estimate)
Fp	216 °C
storage temp.	Store below +30°C.
solubility	almost transparency in Methanol
pka	11.89±0.23(Predicted)
form	Crystalline Powder
color	Light beige to pink-beige
Water Solubility	3.8mg/L at 20℃
BRN	2049542
Stability:	Stable. Incompatible with oxidizing agents.
LogP	274 at 30℃
CAS DataBase Reference	88-58-4(CAS DataBase Reference)
NIST Chemistry Reference	1,4-Benzenediol, 2,5-bis(1,1-dimethylethyl)-(88-58-4)
EPA Substance Registry System	1,4-Benzenediol, 2,5-bis(1,1-dimethylethyl)- (88-58-4)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-22
Safety Statements	26-24/25
WGK Germany	3
RTECS	MX5160000
Autoignition Temperature	790 °F
Hazard Note	Irritant
TSCA	Yes
HS Code	29072900

MSDS Information

Provider	Language
Dibutylhydroquinone	English
SigmaAldrich	English
ACROS	English
ALFA	English

2,5-Di-tert-butylhydroquinone Usage And Synthesis

Chemical Properties	cream or pale brown solid
Uses	2,5-Di-tert-butylhydroquinone is the oxidation substrate used to measure the catalytic activity of the copper(II) enzyme-like catalysts.
Definition	ChEBI: A member of the class of hydroquinones that is benzene-1,4-diol substituted by tert-butyl groups at position 2 and 5.
General Description	Mobilizes Ca²⁺ specifically from the Ins(1,4,5)P₃-sensitive Ca²⁺ stores by inhibiting microsomal and sarcoplasmic reticulum Ca²⁺-ATPase activity. Does not affect mitochondrial Ca²⁺ fluxes or plasma membrane Ca²⁺/Mg²⁺ ATPase activity. Useful for the study of endomembrane Ca²⁺ stores and plasma membrane Ca²⁺ permeability pathways.
Biological Activity	A selective inhibitor of endoplasmic reticulum Ca 2+ -ATPase.
Biochem/physiol Actions	2,5-Di-tert-butylhydroquinone specifically inhibits the sarcoplasmic reticulum (SR) Ca2+ uptake in the rat ventricle.
Purification Methods	Crystallise the hydroquinone from *C6H6 or AcOH. [Beilstein 6 III 4741.]
references	[1]. hasséssian h, vaca l, kunze dl. blockade of the inward rectifier potassium current by the ca(2+)-atpase inhibitor 2',5'-di(tert-butyl)-1,4-benzohydroquinone (bhq). br j pharmacol, 1994, 112(4): 1118-1122. [2]. fusi f, gorelli b, valoti m, et al. effects of 2,5-di-t-butyl-1,4-benzohydroquinone (bhq) on rat aorta smooth muscle. eur j pharmacol, 1998, 346(2-3): 237-243. [3]. fusi f, saponara s, gagov h, et al. 2,5-di-t-butyl-1,4-benzohydroquinone (bhq) inhibits vascular l-type ca(2+) channel via superoxide anion generation. br j pharmacol, 2001, 133(7): 988-996. [4]. jan cr, ho cm, wu sn, et al. mechanism of rise and decay of 2,5-di-tert-butylhydroquinone-induced ca2+ signals in madin darby canine kidney cells. eur j pharmacol, 1999, 365(1): 111-117.

2,5-Di-tert-butylhydroquinone Preparation Products And Raw materials

Raw materials	Hydroquinone-->Isobutylene-->1,4-Benzenediol, 2-(1,1-dimethylethyl)-5-(2-propen-1-yl)--->2,5-Di-tert-butyl-1,4-benzoquinone-->Allyltributyltin
Preparation Products	6-BROMO-1H-INDOLE-2-CARBALDEHYDE-->(6-BROMO-1H-INDOL-2-YL)METHANOL-->6-Bromoindole-2-carboxylic acid-->Ethyl 6-bromoindole-2-carboxylate-->tert-Butylhydroquinone-->2,6-di-tert-butylhydroquinone-->Phenyl-t-butylether-->1,4-Di-t-butyl-2,5-bis(2-methoxyethoxy)benzene, 99+% Redox shuttle ANL-RS2

2,5-DITERTOCTYLHYDROQUINONE ALPHA-[[[2,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXYPHENOXY]CARBONYL]OXY]-2-NITRO-BENZENEACETIC ACID tert-Butylhydroquinone 2,5-BIS(1,1-DIMETHYLBUTYL)-4-METHOXYPHENOL 1,4-BIS(N-OCTYLOXY)-2,5-DI-T-PENTYLBENZENE Cyhalofop-butyl 1,4-DI-TERT-BUTYL-2,5-DIMETHOXYBENZENE 2,6-di-tert-butylhydroquinone Recombinant Human Telomerase 2,5-Di(tert-amyl)hydroquinone 2,5-DI-TERT-BUTYL-4-HYDROXYANISOLE 2,5-Bis(1,1,3,3-tetramethylbutyl)hydroquinone Buprofezin tert-Butanol Hydroquinone 1,4-Dimethoxybenzene 2,6-DIMETHYLHYDROQUINONE DI-TERT-BUTYL ETHER

Email:[email protected] [email protected]

Copyright © 2024 Mywellwork.com All rights reserved.