ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards ent-Voriconazole

ent-Voriconazole

ent-Voriconazole Basic information
Product Name:ent-Voriconazole
Synonyms:ent-Voriconazole;(αS,βR)-α-(2,4-Difluorophenyl)-5-fluoro-β-Methyl-α-(1H-1,2,4-triazol-1-ylMethyl)-4-pyriMidineethanol;(alphaS,betaR)-alpha-(2,4-Difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol;epi-Voriconazole;Voriconazole Impurity 15(Voriconazole EP Impurity D);(2RS,3RS)-α-(2,4-Difluorophrnyl)-5-fluoro-β-menthyl-α-(1H-1,2,4-triazol-1-ylmenthyl)-4-pyrimidineethanol;Voriconazole isomer;Voriconazole EP Impurity D-d3 (Voriconazole Enantiomer-d3)
CAS:137234-63-0
MF:C16H14F3N5O
MW:349.31
EINECS:
Product Categories:Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:137234-63-0.mol
ent-Voriconazole Structure
ent-Voriconazole Chemical Properties
Melting point 130-132°C
Boiling point 508.6±60.0 °C(Predicted)
density 1.42±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka11.54±0.29(Predicted)
form neat
Safety Information
HS Code 2933997500
MSDS Information
ent-Voriconazole Usage And Synthesis
Chemical PropertiesWhite Solid
UsesThe (2S,3R) enantiomer in Voriconazole (V760000) drug substance.
ent-Voriconazole Preparation Products And Raw materials
6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine rac 5-Desfluoro Voriconazole Pyrimidine, 4-chloro-6-(1,1-dibromoethyl)-5-fluoro- Voriconazole Impurity 53 (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride 2-Chloro-6-ethyl-5-fluoro-4-hydroxy pyrimidine ammonium salt 2-Chloro-2',4'-difluoroacetophenone Pyrimidine, 4-bromo-6-(1-bromoethyl)-5-fluoro- DL-10-CAMPHORSULFONIC ACID FENOFIBRIC ACID ETHYL ESTER Pyrimidine, 4,4'-(1,2-dimethyl-1,2-ethanediyl)bis[2,6-dichloro-5-fluoro- (9CI) (2R,3S/2S,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol 1-Butanesulfonic acid, 4-hydroxy-, methyl ester Ethanone, 1-(3,5-difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)- 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone Voriconazole Impurity 16 4-Ethyl-5-fluoropyrimidine 4-Ethyl-5-fluoro-6-hydroxypyrimidine
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