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| | Rufloxacin hydrochloride Basic information |
| Product Name: | Rufloxacin hydrochloride | | Synonyms: | RUFLOXACIN HCL;RUFLOXACIN HYDROCHLORIDE;7h-pyrido(1,2,3-de)(1,4)benzothiazine-6-carboxylicacid,2,3-dihydro-9-fluoro-1;mf-934;RUFLOXACINHYDROCHLORIDE(SUBJECTTOPATENTFREE);2,3-Dihydro-9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acid hydrochloride;3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1;4-benzothiazine-6-carboxylic acid | | CAS: | 106017-08-7 | | MF: | C17H19ClFN3O3S | | MW: | 399.87 | | EINECS: | | | Product Categories: | | | Mol File: | 106017-08-7.mol |  |
| | Rufloxacin hydrochloride Chemical Properties |
| Melting point | 322-324℃ | | storage temp. | -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly, Heated), Water (Very Slightly) | | form | Off-white to light green crystalline solid. | | color | Off-White to Pale Yellow | | CAS DataBase Reference | 106017-08-7(CAS DataBase Reference) |
| Toxicity | LD50 in rats, mice (mg/kg): 285, 224 i.v.; LD50 in rabbits, male, female rats (mg/kg): 660, 631, 501 orally (Cecchetti) |
| | Rufloxacin hydrochloride Usage And Synthesis |
| Description | Rufloxacin hydrochloride is another fluoroquinolone orally active antibacterial
structurally and mechanistically related to temafloxacin and tosufloxacin. It is useful
for the treatment of respiratory and urinary tract infections and also chronic bacterial
prostatitis. Good tissue penetration with long acting activity has been reported. | | Originator | Mediolanum (Italy) | | Uses | Rufloxacin Hydrochloride inhibits human organic cation transporter 1 (hoCT1) (SLC22A1) but not hOCT2 (SLC22A2), and hOCT3 (SLC22A3) expressed in human embryonic kidney cell. | | Brand name | Qari; Monos |
| | Rufloxacin hydrochloride Preparation Products And Raw materials |
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