(-)-Di-p-toluoyl-L-tartaric acid

(-)-Di-p-toluoyl-L-tartaric acid Basic information
Uses
Product Name:(-)-Di-p-toluoyl-L-tartaric acid
Synonyms:(-)-Ditoluoyl-(L)-tartaric acid monohydrate;Di-4-Toluoyl-L-tartaric acid;(-)-2,3-DI-P-TOLUOYL-L-TARTARIC ACID;Di-p-Toluyl-L-Tartaric Acid Anhydrous;(-)-DI-O,O'-P-TOLUOYL-L-TARTARIC ACID;Di-Para-Toluoyl-D-TartaricAcid,Anhydrous;Di-Para-Toluoyl-L-TartaricAcid;Di-P-Toluoyl-L-TartaricAcid(Anhydrous)
CAS:32634-66-5
MF:C20H18O8
MW:386.35
EINECS:251-131-7
Product Categories:chiral;Carboxylic Acids (Chiral);Chiral Building Blocks;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Pharmaceutical Intermediates;FINE Chemical & INTERMEDIATES;Chiral Compounds;Miscellaneous;CHIRAL CHEMICALS;Hydroxy Acids & Deriv.;Carboxylic AcidsAsymmetric Synthesis;Chiral Building Blocks;Chiral Compound;Inhibitors;Chiral Resolution Reagents;Chiral Resolving Reagents;Organic Building Blocks
Mol File:32634-66-5.mol
(-)-Di-p-toluoyl-L-tartaric acid Structure
(-)-Di-p-toluoyl-L-tartaric acid Chemical Properties
Melting point 169-171 °C(lit.)
alpha -142 º (c=10, EtOH)
Boiling point 432.57°C (rough estimate)
density 1.3084 (rough estimate)
refractive index -139 ° (C=1, EtOH)
storage temp. Store below +30°C.
solubility Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka1.46±0.25(Predicted)
form Crystalline Powder
color White to yellow
optical activity[α]20/D 138°, c = 1 in ethanol
Water Solubility soluble
BRN 2022481
CAS DataBase Reference32634-66-5(CAS DataBase Reference)
EPA Substance Registry SystemButanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, [R-(R*,R*)]- (32634-66-5)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36/37-26
WGK Germany 3
TSCA T
HS Code 29181300
MSDS Information
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(-)-Di-p-toluoyl-L-tartaric acid Usage And Synthesis
Uses

(-)-di-p-toluoyl-l-tartaric acid can be used as a chiral resolving agent for the resolution of the racemic bases to isolate the (-)-enantiomeric forms.

Chemical Propertieswhite to light yellow crystal powde
UsesEscitalopram intermediate
Uses(-)-O,O’-Di-p-toluoyl-L-tartaric Acid is a useful reagent for the preparation of the upadacitinib salt compound.
UsesInhibitor of enzyme
General Description(-)-O,O′-Di-p-toluoyl-L-tartaric acid is a O,O′-diacyl tartaric acid derivative that can be prepared by the resolution of its racemate in the presence of cinchonine.
(-)-Di-p-toluoyl-L-tartaric acid Preparation Products And Raw materials
R-VENLAFAXINE-DI-P-TOLUOYL-L-TARTRATE SALT Benzoyl peroxide (R)-(+)-2-BENZYLOXYPROPIONIC ACID O-Phthalimide (+)-Dibenzoyl-D-tartaric acid Dimethyl sulfone BENZOYL LACTIC ACID (S)-3-(BENZYLOXY)BUTANOIC ACID 3-(BENZYLOXY)-2-HYDROXYPROPANOIC ACID Folic acid (-)-DIACETYL-L-TARTARIC ACID DI-P-TOLUOYL-L-TARTARIC ACID (-)-Dibenzoyl-L-tartaric acid monohydrate D(-)-Tartaric acid Calcium folinate L(+)-Tartaric acid phosphoric acid S-VENLAFAXINE-DI-P-TOLUOYL-L-TARTRATE SALT

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