alpha-Methyl-4-biphenylacetic acid

alpha-Methyl-4-biphenylacetic acid Basic information

Product Name:	alpha-Methyl-4-biphenylacetic acid
Synonyms:	alpha-Methyl-4-biphenylacetic acid;2-(Biphenyl-4-yl)propanoic acid;LY-71130;p-Phenylhydroatropic acid;α-Methyl-4-biphenylacetic acid;α-Methylbiphenyl-4-acetic acid;Flurbiprofen Related CoMpound A (Biprofen);(2RS)-2-(Biphenyl-4-yl)propanoic acid
CAS:	6341-72-6
MF:	C15H14O2
MW:	226.27
EINECS:
Product Categories:	Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	6341-72-6.mol

alpha-Methyl-4-biphenylacetic acid Chemical Properties

Melting point	168-169 °C
Boiling point	388.3±21.0 °C(Predicted)
density	1.134±0.06 g/cm3(Predicted)
solubility	DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly, Heated)
form	neat
pka	4.34±0.10(Predicted)

Safety Information

RIDADR	UN 2811 6.1 / PGIII
HS Code	2916399000

MSDS Information

alpha-Methyl-4-biphenylacetic acid Usage And Synthesis

Uses	A metabolite of Isopropylbiphenyl, a COX-2 selective inhibitor. Also an impurity of Flurbiprofen (F598700).
Synthesis Reference(s)	Synthesis, p. 456, 1982 DOI: 10.1055/s-1982-29832

alpha-Methyl-4-biphenylacetic acid Preparation Products And Raw materials

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