4,6-O-Ethylidene-alpha-D-glucose

4,6-O-Ethylidene-alpha-D-glucose Basic information
Product Name:4,6-O-Ethylidene-alpha-D-glucose
Synonyms:(2R,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propanal;(4aR,6S,7R,8R,8aS)-2-Methylhexahydropyrano[3,2-d][1,3]dioxine-6,7,8-triol;(4AR,7R,8R,8aS)-2-Methylhexahydropyrano-[3,2-d][1,3]dioxine-6,7,8-triol;NSC 89726;-D-glucopyranose;4,6-O-Ethylidene-α;4,6-O-ETHYLIDENE-A-D-GLUCOSE;4,6-O-ETHYLIDENE-ALPHA-D-GLUCOPYRANOSE
CAS:13224-99-2
MF:C8H14O6
MW:206.19
EINECS:236-198-2
Product Categories:Carbohydrate Synthesis;Specialty Synthesis;Sugars, Carbohydrates & Glucosides;Biochemistry;Sugars;Monosaccharides;Glucose;O-Substituted Sugars
Mol File:13224-99-2.mol
4,6-O-Ethylidene-alpha-D-glucose Structure
4,6-O-Ethylidene-alpha-D-glucose Chemical Properties
Melting point 168-170 °C(lit.)
Boiling point 386.6±42.0 °C(Predicted)
density 1.446±0.06 g/cm3(Predicted)
Fp >110°(230°F)
solubility Ethanol, Water
pka12.01±0.70(Predicted)
form Powder
color White to Off-white
Water Solubility almost transparency
LogP0.54
CAS DataBase Reference13224-99-2(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29400090
MSDS Information
ProviderLanguage
SigmaAldrich English
4,6-O-Ethylidene-alpha-D-glucose Usage And Synthesis
Uses4,6-O-Ethylidene-D-glucose is an intermediate in synthesizing α-Etoposide (E933745), which is a cytotoxic agent (anticancer drug), which belongs to the drug type topoisomerase inhibitor. It is also an antineoplastic drug.
4,6-O-Ethylidene-alpha-D-glucose Preparation Products And Raw materials
Raw materialsDiethyl ether-->Sulfuric acid-->Ammonium hydroxide-->Acetone-->Paraldehyde-->DEXTROSE
Glucose oxidase LIQUID GLUCOSE 4-NITROPHENYL 3-O-(2',3',4',6'-TETRA-O-4-METHOXYBENZYL-ALPHA-D-GLUCOPYRANOSYL)-4,6-BENZYLIDENE-ALPHA-D-GLUCOPYRANOSIDE D(+)-Glucose Diethylenetriamine 4-Nitrophenyl4,6-benzylidene-a-D-glucopyranoside CORN SYRUP 1-Hydroxyethylidene-1,1-diphosphonic acid Blood Glucose Hydroxyethyl Cellulose Ethyl maltol Bis(methyl 4,6-O-benzylidene-2-o-thiocarbonyl-alpha-D glucopyranoside) disulfide METHYL 4,6-O-BENZYLIDENE-ALPHA-D-GLUCOPYRANOSIDE 4,6-O-Ethylidene-alpha-D-glucose (2-O-BENZYL-4,6-O-BENZYLIDENE) METHYL-ALPHA-D-GLUCOPYRANOSIDE N-NITROSODIETHYLAMINE 1,4,7,10,13-Pentaazatridecane Diethylstilbestrol

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