ChemicalBook Product Catalog Organic Chemistry Organometallic compounds Organotin 2-(Tributylstannyl)pyrimidine

2-(Tributylstannyl)pyrimidine

2-(Tributylstannyl)pyrimidine Basic information
Product Name:2-(Tributylstannyl)pyrimidine
Synonyms:2-(tri-n-butylstannyl)pyrimidine;2-(Tributylstannyl)pyrimidine ,97%;(Pyrimidin-2-yl)tributylstannane;2-(Tributylstannanyl)pyrimidine;Tributyl(2-pyrimidyl)stannane;PyriMidine,2-(tributylstannyl)-;(Pyrimidin-2-yl)tributylstannane, 2-(Tributylstannyl)-1,3-diazine;2-tributyltinpyrMidine
CAS:153435-63-3
MF:C16H30N2Sn
MW:369.13
EINECS:
Product Categories:organic tin;Organostannes;Pyrimidine;Tributylstanny
Mol File:153435-63-3.mol
2-(Tributylstannyl)pyrimidine Structure
2-(Tributylstannyl)pyrimidine Chemical Properties
Boiling point 381.2±25.0 °C(Predicted)
density 1.164 g/mL at 25 °C
refractive index n20/D1.512
Fp >110℃
storage temp. Sealed in dry,2-8°C
solubility soluble in Methanol; Ethyl Acetate; Dichloromethane; Chloroform; DMF; DMSO
form liquid
pka1.42±0.33(Predicted)
color Colourless
Safety Information
Hazard Codes Xi,T,N
Risk Statements 21-25-36/38-48/23/25-50/53
Safety Statements 36/37/39-45-60-61-35
RIDADR UN 2788 6.1 / PGIII
WGK Germany 3
HazardClass IRRITANT, TOXIC, KEEP COLD
HS Code 29339900
MSDS Information
2-(Tributylstannyl)pyrimidine Usage And Synthesis
Chemical PropertiesClear colorless liquid
Uses2-(Tributylstannyl)pyrimidine is an organotin compound used in Stille coupling reaction. This can be used as one of the precursors in the synthesis of 2-aminopyridine oxazolidinones as potent and selective tankyrase (TNKS) inhibitors and the synthesis of canagliflozin, a novel inhibitor for sodium-dependent glucose cotransporter.
It can also be used in the preparation of various (2-pyrimidyl)silanes.
2-(Tributylstannyl)pyrimidine Preparation Products And Raw materials
Preparation ProductsSCH 486757-->3-fluoro-2-(pyrimidin-2-yl)benzonitrile
2-(Tributylstannyl)pyrimidine
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