ChemicalBook Product Catalog Biochemical Engineering Inhibitors Microbiology Reverse Transcriptase Inhibitors DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE

DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE

DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE Basic information
Product Name:DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE
Synonyms:DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE;Dapivirine;Dapivirine TMC120, AIDS-105293;4-[[4-[(2,4,6-TriMethylphenyl)aMino]-2-pyriMidinyl]aMino]benzonitrile;R 147681;TMC 120R147681;Benzonitrile, 4-[[4-[(2,4,6-triMethylphenyl)aMino]-2-pyriMidinyl]aMino]-;Dapivirine,TMC-120
CAS:244767-67-7
MF:C20H19N5
MW:329.4
EINECS:
Product Categories:pharmacetical;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Non-nucleoside Reverse Transcriptase;Pharmaceuticals;Inhibitors;API
Mol File:244767-67-7.mol
DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE Structure
DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE Chemical Properties
Melting point 218-222°C
Boiling point 557.9±60.0 °C(Predicted)
density 1.23±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO (Slightly), Methanol (Slightly)
pka4.74±0.10(Predicted)
form Solid
color Off-White to Light Beige
Safety Information
MSDS Information
DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE Usage And Synthesis
Chemical PropertiesLight Beige Solid
UsesNon-nucleoside Reverse Transcriptase inhibitor. An antiviral agent.
targetHIV reverse transcriptase
DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE Preparation Products And Raw materials
BEZ235 (NVP-BEZ235, Dactolisib) Fedratinib (SAR302503, TG101348) Apitolisib (GDC-0980, RG7422) VE 822 Y27632 (hydrochloride) RILPIVIRINE FUMARATE SALT [1:1] RILPIVIRINE HCL DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE 4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethyl-phenyl]amino]pyrimidin-2-yl]amino]benzonitrile
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