(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide

(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide Basic information
Product Name:(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide
Synonyms:(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide;1-(4-AcetaMido-2-acetylphenoxy)-2-hydroxy-3-isopropylaMinopropane;DL-3'-Acetyl-4'-[2-hydroxy-3-(isopropylaMino)propoxy]acetanilide;Acebutolol EP IMpurity B;Acebutolol Impurity B HCl;rac Diacetolol;N-{3-Acetyl-4-{(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy}phenyl}acetamide;Acebutolol Impurity 2 Monomer
CAS:22568-64-5
MF:C16H24N2O4
MW:308.37
EINECS:245-088-3
Product Categories:Amines;Aromatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:22568-64-5.mol
(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide Structure
(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide Chemical Properties
Melting point 128 - 131°C
storage temp. Refrigerator, under inert atmosphere
solubility Chloroform (Very Slightly), DMSO (Slightly), Methanol (Slightly)
form neat
color Off-White to Light Yellow
Safety Information
HS Code 2933599550
MSDS Information
(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide Usage And Synthesis
UsesThe principal metabolite of Acebutolol (A123800) with less β-adrenoceptor blocking potency but greater cardioselectivity (atrial relative to tracheal tissue).
UsesThe principal metabolite of Acebutolol (A123800) with less β-adrenoceptor blocking potency but greater cardioselectivity (atrial relative to tracheal tissue. Acebutolol EP Impurity B.
(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide Preparation Products And Raw materials
Acebutolol EP Impurity D N,N'-[(2-Hydroxypropane-1,3-diyl)bis[oxy(3-acetyl-1,4-phenylene)]]dibutanaMide Acebutolol hydrochloride rac N-Desisopropyl-N-ethyl Acebutolol (±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide monohydrochloride Acebutolol DiMer IMpurity Acebutolol EP IMpurity J Acebutolol Impurity E rac Des(isopropylaMino) Acebutolol Diol Acebutolol Acebutolol Impurity G rac 3-Deacetyl-3-butanoyl Acebutolol Hydrochloride rac N-Desbutyroyl Acebutolol Acebutolol Impurity H N-[3-acetyl-4-(oxiranylmethoxy)phenyl]butyramide 2-Acetyl-4-butyramidophenol

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