ChemicalBook Product Catalog Analytical Chemistry Standard 2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro-

2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro-

2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro- Basic information
Product Name:2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro-
Synonyms:2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro-;Apixaban Impurity 101;1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone
CAS:1801881-15-1
MF:C11H11ClN2O
MW:222.67
EINECS:
Product Categories:
Mol File:1801881-15-1.mol
2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro- Structure
2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro- Chemical Properties
Boiling point 394.8±42.0 °C(Predicted)
density 1.34±0.1 g/cm3(Predicted)
pka4.96±0.10(Predicted)
Safety Information
MSDS Information
2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro- Usage And Synthesis
Uses1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone is an impurity of Apixaban (A726700(P)), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Apixaban is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro- Preparation Products And Raw materials
Apixaban-13C-D3 Apixaban Impurity 15 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one Apixaban Impurity 102 Apixaban Impurity 22 Apixaban Impurity 7 Apixaban Impurity 51 1-(4-Methoxyphenyl)-6-(4-iodophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, 2-hydroxy-1-methylethyl ester 4-Pyridineacetic acid, 1,2,5,6-tetrahydro-3-hydroxy-α,2-dioxo-1-[4-(2-oxo-1-piperidinyl)phenyl]- Apixaban Impurity 8 Hydroxy O-Desmethyl Apixaban ethyl (E)-2-(2-(4-methoxyphenyl)hydrazono)propanoate Apixaban Impurity 24 Apixaban Impurity 52 O-DesmethylApixabanSulphateNa Hydroxy O-Desmethyl Apixaban Sulfate 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, 2-hydroxypropyl ester
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