ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Arginine derivatives POLY-L-ARGININE HYDROCHLORIDE

POLY-L-ARGININE HYDROCHLORIDE

POLY-L-ARGININE HYDROCHLORIDE Basic information
Product Name:POLY-L-ARGININE HYDROCHLORIDE
Synonyms:POLY-L-ARGININE HCL;POLY-L-ARGININE HYDROCHLORIDE;poly-L-arginine hcl mol wt 70000-150000;poly-L-arginine hydrochloride mol. wt.*5000-15000;POLY-L-ARGININE HCL MOL WT 15000-70000;mw10000-20000;L-ARGININE, HOMOPOLYMER, HYDROCHLORIDE;POLY-L-ARGININE HCL MOL WT 15000-700
CAS:26982-20-7
MF:C6H14N4O2
MW:174.2
EINECS:
Product Categories:Amino Acids;Homopolymers;Polyamino Acids
Mol File:26982-20-7.mol
POLY-L-ARGININE HYDROCHLORIDE Structure
POLY-L-ARGININE HYDROCHLORIDE Chemical Properties
storage temp. -20°C
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
POLY-L-ARGININE HYDROCHLORIDE Usage And Synthesis
UsesPoly-L-arginine hydrochloride has been used:
  • to generate complex with stimulatory RNA isRNA9.2 as in neutrophils
  • used in ribosomal RNA transfection into human monocytic THP-1 cells
  • for coating alginate capsule beads

UsesPoly-L-arginine hydrochloride has been used:
  • as polyelectrolyte solution in the synthesis of biodegradable capsules
  • as layer constituent, in the preparation of layer by layer (LbL) assembly of multilayer biodegradable shells
  • in assay for the determination of binding activity of C-reactive protein for polycationic ligands

General DescriptionPoly-L-arginine hydrochloride (PLA) is a homopolyamino acid. PLA enhances membrane permeability compared to poly-L-lysine. It has applications as drug carrier, neuroprotective agent and in anticancer vaccines preparations. Peptide vaccines in conjugation with PLA promotes antigen-presenting cells (APCs) to generate T cell and elicit immunostimulant functionality.
Biochem/physiol ActionsPoly-L-arginine (PLA) possesses anti-bacterial activity. It has a greater capacity to enhance membrane permeability. PLA at lower concentration enhances cell proliferation and at higher concentration acts as antiproliferative agent.
POLY-L-ARGININE HYDROCHLORIDE Preparation Products And Raw materials
Aluminum acetylacetonate METHYL ISOCYANOACETATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) N-BUTYLISOCYANIDE PHENYLSELENOL Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) SALCOMINE 2,4-PENTANEDIONE, SILVER DERIVATIVE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Tosylmethyl isocyanide COBALT(II) ACETYLACETONATE Cupric acetylacetonate Ethyl isocyanoacetate TERT-BUTYL ISOCYANIDE Ferric acetylacetonate COBALT ETHYLENE DIAMINE CHLORIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
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