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| | (±)-Cloprostenol sodium salt Basic information |
| Product Name: | (±)-Cloprostenol sodium salt | | Synonyms: | 15-EPI CLOPROSTENOL;15(S)-CLOPROSTENOL;16-(3-CHLOROPHENOXY)-9,11,15R-TRIHYDROXY-17,18,19,20-TETRANORPROSTA-5Z,13E-DIEN-1-OIC ACID SODIUM SALT;(+)-16-M-CHLOROPHENOXY TETRANOR PROSTAGLANDIN F2ALPHA SODIUM SALT;7-(2-[4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl)-5-heptenoic acid;(5Z)-rel-Cloprostenol SodiuM;DL-Cloprostenol sodiuM;(+/-)-16-(3-Chlorophenoxy)-9,11,15R-trihydroxy-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid hydrate sodium salt | | CAS: | 55028-72-3 | | MF: | C22H30ClNaO6 | | MW: | 448.92 | | EINECS: | 259-439-3 | | Product Categories: | Other APIs;Pharmaceuticals;Pharmaceutical Raw Materials;Prostaglandins;Chiral Reagents;Intermediates & Fine Chemicals | | Mol File: | 55028-72-3.mol |  |
| | (±)-Cloprostenol sodium salt Chemical Properties |
| Melting point | 68-70 °C | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | H2O: >10 mg/mL | | form | solid | | color | light brown | | InChIKey | IFEJLMHZNQJGQU-KXXGZHCCSA-M | | CAS DataBase Reference | 55028-72-3(CAS DataBase Reference) |
| | (±)-Cloprostenol sodium salt Usage And Synthesis |
| Description | ±)-Cloprostenol sodium salt is the d-enantiomer of Cloprostenol (C587300), an aryl-oxymethyl analog of prostaglandin F2α. | | Uses | (±)-Cloprostenol sodium salt is a prostaglandin that dissolves the corpus luteum of cattle and is used as a veterinary drug. | | Brand name | Estrumate(Bayer Animal
Health). | | General Description | Cloprostenol sodium (Estrumate)is available as the sodium salt from Bayer AgriculturalDivision or Bayvet Division of Miles Laboratory as an aqueoussolution containing 250 mg/mL. | | Biological Activity | Water-soluble prostaglandin F 2 α (PGF 2 α ) analog; acts as a potent FP receptor agonist (EC 50 = 0.84 nM). Potently inhibits differentiation of adipocyte precursor cells. Luteolytic agent in vivo . | | Veterinary Drugs and Treatments | Cloprostenol is approved for use in beef or dairy cattle to induce
luteolysis. It is recommended by the manufacturer for unobserved
or undetected estrus in cows cycling normally, pyometra or chronic
endometritis, expulsion of mummified fetus, luteal cysts, induced
abortions after mismating, and to schedule estrus and ovulation for
controlled breeding.
Cloprostenol has been used in dogs for pregnancy termination
and treatment of open pyometra. The use of cloprostenol for pyometra
is controversial as some believe dinoprost (PGF2alpha) is
more effective and has fewer adverse effects than cloprostenol. | | Solubility in water | Soluble in H2O. |
| | (±)-Cloprostenol sodium salt Preparation Products And Raw materials |
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