3-Methoxysalicylaldehyde

3-Methoxysalicylaldehyde Basic information
Product Name:3-Methoxysalicylaldehyde
Synonyms:TIMTEC-BB SBB000109;2-Hydroxy-3-methoxybenzaldehyde, 2-Hydroxy-m-anisaldehyde, 3-Methoxysalicylaldehyde;2-HYDROXY-3-METHOXYBENZALDEHYDE / O-VANILLIN;Adjacent vanillin;3-Methoxysalicyladehyde;NC 005;NSC 2150;2-Hydroxy-3-Methoxybenzaldehyde-13C6,d3
CAS:148-53-8
MF:C8H8O3
MW:152.15
EINECS:205-715-3
Product Categories:Aromatics;Aldehydes;Building Blocks;C8;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Aromatic Aldehydes & Derivatives (substituted)
Mol File:148-53-8.mol
3-Methoxysalicylaldehyde Structure
3-Methoxysalicylaldehyde Chemical Properties
Melting point 40-42 °C (lit.)
Boiling point 265-266 °C (lit.)
density 1.2143 (rough estimate)
refractive index 1.4945 (estimate)
Fp >230 °F
storage temp. Store below +30°C.
solubility Chloroform (Sparingly), Methanol (Slightly)
form Low Melting Solid
pkapK1:7.912 (25°C)
color Pale yellow to brown
Water Solubility slightly soluble
Sensitive Air Sensitive
BRN 471913
Stability:Hygroscopic
LogP1.370
CAS DataBase Reference148-53-8(CAS DataBase Reference)
NIST Chemistry ReferenceBenzaldehyde, 2-hydroxy-3-methoxy-(148-53-8)
EPA Substance Registry SystemBenzaldehyde, 2-hydroxy-3-methoxy- (148-53-8)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 23-36-24/25-36/37/39-27-26
WGK Germany 3
RTECS CU6530000
10-23
TSCA Yes
HS Code 29124900
MSDS Information
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3-Methoxysalicylaldehyde English
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3-Methoxysalicylaldehyde Usage And Synthesis
Chemical PropertiesPale yellow to brown low melting solid
Useso-Vanillin has been used to study the solvent-free reaction between o-vanillin and p-toluidine using NMR, DSC and XRD analysis. It was used in the synthesis of new ligand for Fe(III) and Al(lII).
Useso-Vanillin has been used to study the solvent-free reaction between o-vanillin and p-toluidine using NMR, DSC and XRD analysis. It was used in the synthesis of new ligand for Fe(III) and Al(lII). It is also used in the study of mutagenesis and as a synthetic precursor for pharmaceuticals.
UsesA positional isomer of Vanillin. o-Vanillin is a more potent antioxidant than Vanillin.
DefinitionChEBI: A member of the class of benzaldehydes that is salicylaldehyde substituted by a methoxy group at position 3.
Hazard ortho-Vanillin is harmful if ingested, irritating to eyes, skin and respiratory system, but has an unmistakable high LD50 of 1330 mg/kg in mice.
Biochem/physiol Actionso-Vanillin induces DNA damage as detected by comet assay.
5-Methoxysalicylaldehyde 4-(phenylthio)semicarbazone 2-HYDROXY-5-METHOXYBENZALDEHYDE = 5-METHOXYSALICYLALDEHYDE Isovanillin 2,6-Dimethoxybenzaldehyde (+)-Bicuculline 3-NITRO-5-METHOXYSALICYLALDEHYDE,3-NITRO-5-METHOXYSALICYLALDEHYDE 97% 3-Methoxysalicylic acid (Trifluoromethoxy)benzene 3,7-Dimethyl-7-hydroxyoctanal 2-Hydroxy-5-Methylbenzaldehyde (5-Methoxysalicylaldehyde) 3-Methoxysalicylaldehyde Ethyl vanillin 2-Hydroxy-4-methoxybenzaldehyde(4-Methoxysalicylaldehyde) 3,5-Dimethoxybenzaldehyde Cuminaldehyde CHLOROPHOSPHONAZO III o-Anisaldehyde 3-Methoxybenzaldehyde

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