FUMITREMORGIN C

FUMITREMORGIN C Basic information
Product Name:FUMITREMORGIN C
Synonyms:FuMitreMorgin CFuMitreMorg;(5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione;12alpha-Fumitremorgin C;5H,14H-Pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione,1,2,3,5a,6,11,12,14a-octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-,(5aS,12S,14aS)-;Fumitremorgin C, Aspergillus. fumigatus - CAS 118974-02-0 - Calbiochem;Fumitremorgin C, 98%, from Aspergillus fumigatus;12α-Fumitremorgin C;Fumitremorgin C, from Aspergillus fumigatus
CAS:118974-02-0
MF:C22H25N3O3
MW:379.45
EINECS:
Product Categories:
Mol File:118974-02-0.mol
FUMITREMORGIN C Structure
FUMITREMORGIN C Chemical Properties
Melting point 259.5-260.5℃
Boiling point 642.9±55.0 °C(Predicted)
density 1.34±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility acetonitrile: 5 mg/mL, soluble
pka17.16±0.40(Predicted)
form solid
color White to light brown
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 2941900000
MSDS Information
FUMITREMORGIN C Usage And Synthesis
UsesFumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has determined fumitremorgin C as a potent inhibitor of the breast cancer resistance protein BCRP/ABCG2 multidrug transporter.
UsesFumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has determined fumitremorgin C as a potent inhibitor of the breast cancer resistance protein BCRP/ABCG2 multidrug transporter.
DefinitionChEBI: An organic heteropentacyclic compound that is a mycotoxic indole alkaloid produced by several fungi. A potent and specific inhibitor of the breast cancer resistance protein multidrug transporter.
General DescriptionA cell-permeable indolyldiketopiperazinyl mycotoxin that inhibits BCRP/ABCG2 (breast cancer resistance protein/ATP-binding cassette G2) multidrug transport activity. Also acts as a potent and specific chemosenzitizing agent.
Biochem/physiol ActionsCell permeable: yes
targetAntifection | P-gp
storage+4°C
FUMITREMORGIN C Preparation Products And Raw materials
2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Variegated toxin Hydroxyecdysone (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one Artemether beta-Sitosterol hydroxygenkwanin alpha-Terpineol beta-Eudesmol MOSLOFLAVONE alpha-Cyperone tetrahydroharmine 5-(DIISOPROPYLAMINO)AMYLAMINE (R)-HEXAHYDROPYRROLO[1,2-A]PYRAZIN-1(2H)-ONE FUMITREMORGIN C CYCLO(-GLY-TRP)

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