|
| | tert-butyl 2-((4R,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl- 4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Basic information |
| Product Name: | tert-butyl 2-((4R,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl- 4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate | | Synonyms: | tert-butyl 2-((4R,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl- 4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate;Atorvastatin calcium-27;Atorvastatin impurity 26/(3R,5S)-Atorvastatin Acetonide tert-Butyl Ester/(4R,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl 1,3-Dioxane-4-acetic Acid 1,1-Dimethylethyl Ester;1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)-;Atorvastatin calcium impurity 43 | | CAS: | 947249-30-1 | | MF: | C40H47FN2O5 | | MW: | 654.81 | | EINECS: | | | Product Categories: | | | Mol File: | 947249-30-1.mol |  |
| | tert-butyl 2-((4R,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl- 4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Chemical Properties |
| Boiling point | 678.0±55.0 °C(Predicted) | | density | 1.14±0.1 g/cm3(Predicted) | | pka | 13.57±0.70(Predicted) |
| | tert-butyl 2-((4R,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl- 4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Usage And Synthesis |
| Uses | (3R,5S)-Atorvastatin Acetonide tert-Butyl Ester is enantiomer of 10-trans-Atorvastatin Acetonide tert-Butyl Ester (A791805), which is an intermediate in the preparation of Atorvastatin 10-Trans, and impurity of Atorvastatin (A791750) that is a selective inhibitor of HMG-CoA reductase. |
| | tert-butyl 2-((4R,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl- 4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Preparation Products And Raw materials |
|
