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Tofacitinib Impurity 77

Tofacitinib Impurity 77 Basic information
Product Name:Tofacitinib Impurity 77
Synonyms:Tofatinib impurity;3-((3R,4R)-4-methyl-3-(methyl(6-oxo-6,7-dihydro-5H-pyrrolo[2,3-d] pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile;Tofacitinib metabolite-1;1-Piperidinepropanenitrile, 3-[(6,7-dihydro-6-oxo-5H-pyrrolo[2,3-d]pyrimidin-4-yl)methylamino]-4-methyl-β-oxo-, (3R,4R)-;Azilsartan medoxomil impurity322;Tofatinib Impurity 32;Tofatinib impurity 38
CAS:1640971-51-2
MF:C16H20N6O2
MW:328.38
EINECS:
Product Categories:
Mol File:1640971-51-2.mol
Tofacitinib Impurity 77 Structure
Tofacitinib Impurity 77 Chemical Properties
Boiling point 640.4±55.0 °C(Predicted)
density 1.312±0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
pka6.05±0.60(Predicted)
Safety Information
MSDS Information
Tofacitinib Impurity 77 Usage And Synthesis
Tofacitinib Impurity 77 Preparation Products And Raw materials
Raw materials4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine Tofacitinib Impurity 2 N-Hydroxysuccinimide CYANOACETIC ACID-OSU (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Tofacitinib Benzyl chloride (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride Malonyl chloride (3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine hydrochloride 3-PiperidinaMine, 1-acetyl-N,4-diMethyl-N-1H-pyrrolo[2,3-d]pyriMidin-4-yl-, (3R,4R)- (9CI) 4-Amino-2,6-dichloropyrimidine N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine Tofacitinib Impurity 85 N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine BENZYL ETHYL ETHER 4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE
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