(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER

(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER Basic information
Product Name:(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER
Synonyms:(R)-METHYL-O-ISOPROPYLIDENE GLYCERATE;(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER;(R)-2,2-DIMETHYL-[1,3]DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER;(R)-(+)-2,2-DiMethyl-1,3-dioxolane-4-carboxylic acid Methylesther;(R)-(+)-2,2-diMethyl-1,3-dioxolan-4-carboxylic acid Methyl ester;Methyl (R)-(+)-2,2-diMethyl-1,3-dioxolane-4-carboxylate 98%;3-METHOXY-5,5,8,8-...;(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID
CAS:52373-72-5
MF:C7H12O4
MW:160.17
EINECS:
Product Categories:Chiral Reagents;Heterocycles;pharmacetical;chiral;Heterocyclic Building Blocks;Intermediates;Chiral Reagent;Chiral Building Blocks;Dioxanes & Dioxolanes;Dioxolanes;Esters (Chiral);Synthetic Organic Chemistry
Mol File:52373-72-5.mol
(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER Structure
(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER Chemical Properties
Boiling point 70-75 °C/10 mmHg (lit.)
density 1.106 g/mL at 25 °C (lit.)
refractive index n20/D 1.426
Fp 173 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
form Oil
color Yellow
optical activity[α]20/D +8.5°, c = 1.5 in acetone
BRN 4292353
InChIKeyDOWWCCDWPKGNGX-RXMQYKEDSA-N
CAS DataBase Reference52373-72-5(CAS DataBase Reference)
Safety Information
Safety Statements 23-24/25
WGK Germany 3
10-23
HS Code 29329990
MSDS Information
ProviderLanguage
SigmaAldrich English
(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER Usage And Synthesis
Chemical PropertiesColorless to light yellowliqui
Uses(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Methyl Ester is a dioxolane derivative used in the preparation of matrix metalloproteinases (MMP) inhibitors.
UsesMethyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate may be used as a starting material to synthesize (2R)-[1-2H2]-glycerol, a probe to study the stereochemistry of glycerol metabolism in Streptomyces cattleya. It may also be used to synthesize organic building blocks like (R)-2,3-dihydroxy-3-methylbutyl toluene-p-sulfonate and (2S,8R)-2-amino-8-[(R) 2,2-dimethyl-1,3-dioxolan-4-yl]-8-oxooctanoic acid.
(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Preparation Products(R)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid-->(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol-d2
RARECHEM EM WB 0228 DIKEGULAC DIHYDRAT DIKEGULAC ACID D-ERYTHRURONOLACTONE ACETONIDE 5-BROMO-5-DEOXY-2,3-O-ISOPROPYLIDENE-D-RIBONOLACTONE (4R,5R)-4,5-DIETHOXYCARBONYL-2,2-DIMETHYL DIOXOLANE RARECHEM AL BP 0891 (2R,3R)-2,3-O-(1-PHENYLETHYLIDENE)-L-TARTARIC ACID DIMETHYL ESTER Dikegulac sodium 2,3-O-ISOPROPYLIDENE-L-LYXONO-1,4-LACTONE 5-O-(TERT-BUTYLDIMETHYLSILYL)-2,3-O-ISOPROPYLIDENE-D-RIBONIC ACID GAMMA-LACTONE (4R,5R)-2,2-DIMETHYL-1,3-DIOXOLANE-4,5-DICARBOXYLIC ACID DIMETHYL ESTER Methyl (4R,5S)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate 2,3-CYCLOHEXYLIDENE-D-RIBONIC ACID GAMMA-LACTONE 2,3-O-Isopropylidene-D-ribonic gamma-lactone 6-FMOC-AMINO-6-DEOXY-2,3-O-ISOPROPYLIDENE-ALPHA-L-XYLO-2-HEXULOFURANOZONIC ACID (R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER 2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonicacidmonohydrate

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