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2-Hydrazino-4-(trifluoromethyl)pyrimidine

2-Hydrazino-4-(trifluoromethyl)pyrimidine Basic information
Product Name:2-Hydrazino-4-(trifluoromethyl)pyrimidine
Synonyms:BUTTPARK 27\08-68;1-[4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL]HYDRAZINE;2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIMIDINE;N-[4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL]HYDRAZINE;4-(Trifluoromethyl)pyrimidin-2-ylhydrazine 97%;2-Hydrazino-4-(trifluoromethyl)pyrimidine ,99%;4-(Trifluoromethyl)pyrimidin-2-ylhydrazine;2-Hydrazino-4-(trifluoromethyl)pyrimidine, 2-Hydrazino-4-(trifluoromethyl)-1,3-diazine
CAS:197305-97-8
MF:C5H5F3N4
MW:178.12
EINECS:
Product Categories:Building Blocks;Heterocyclic Building Blocks;Pyrimidines
Mol File:197305-97-8.mol
2-Hydrazino-4-(trifluoromethyl)pyrimidine Structure
2-Hydrazino-4-(trifluoromethyl)pyrimidine Chemical Properties
Melting point 99-101 °C(lit.)
Boiling point 187.4±50.0 °C(Predicted)
density 1.62±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Soluble in aqueous acid.
pka5.63±0.40(Predicted)
form powder to crystal
color White to Orange to Green
Safety Information
Hazard Codes T,Xi
Risk Statements 23/24/25-36/37/38
Safety Statements 26-36/37/39-45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
HazardClass IRRITANT, IRRITANT-HARMFUL
HazardClass 6.1
PackingGroup III
HS Code 29335990
MSDS Information
ProviderLanguage
SigmaAldrich English
2-Hydrazino-4-(trifluoromethyl)pyrimidine Usage And Synthesis
Chemical PropertiesWhite to light yellow solid
Uses2-Hydrazino-4-(trifluoromethyl)pyrimidine may be used as a derivatization reagent for the simultaneous determination of testosterone (T) and dihydrotestosterone (DHT) in murine tissue and serum. Synthesis of organohydrazide chelate complexes of rhenium and technetium. Preparation of 1-(4-methoxyphenyl)ethanone [(4-trifluoromethyl)pyrimidine-2-yl]hydrazone (NAS-75).
Uses2-Hydrazino-4-(trifluoromethyl)pyrimidine may be used in the following studies:
  • As derivatization reagent for the simultaneous determination of testosterone (T) and dihydrotestosterone (DHT) in murine tissue and serum samples by liquid chromatography-electrospray ionization-tandem mass spectrometry.
  • Synthesis of organohydrazide chelate complexes of rhenium and technetium, having a metal-nitrogen-nitrogen linkage.
  • Preparation of 1-(4-methoxyphenyl)ethanone [(4-trifluoromethyl)pyrimidine-2-yl]hydrazone (NAS-75).
Methyl 2-hydrazino-4-(trifluoromethyl)pyrimidine-5-carboxylate, 95+%,METHYL 2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE [4-(3-METHOXY-PHENYL)-6-TRIFLUOROMETHYL-PYRIMIDIN-2-YL]-HYDRAZINE [4-(4-METHOXY-PHENYL)-6-TRIFLUOROMETHYL-PYRIMIDIN-2-YL]-HYDRAZINE ETHYL 2-(2-[3-(CHLOROMETHYL)BENZOYL]HYDRAZINO)-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE (4-FURAN-2-YL-6-TRIFLUOROMETHYL-PYRIMIDIN-2-YL)-HYDRAZINE AKOS B021295 4-CHLOROBENZYL 2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE (4-THIOPHEN-2-YL-6-TRIFLUOROMETHYL-PYRIMIDIN-2-YL)-HYDRAZINE METHYL 2-(2-([2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]CARBONYL)HYDRAZINO)-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE AKOS B020789 ETHYL 2-OXO-2-(2-[4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL]HYDRAZINO)ACETATE ETHYL 2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Fluorocytosine 2-Hydrazino-4-(trifluoromethyl)pyrimidine 4-CHLOROBENZYL 2-[2-(2-CHLOROACETYL)HYDRAZINO]-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Pirimiphos-methyl BENZYL 2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE ETHYL 2-[2-(2-CHLOROACETYL)HYDRAZINO]-4-(TRIFLUOROMETHYL)-5-PYRIMIDINECARBOXYLATE
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