2-Amino-4-nitro anisidine

2-Amino-4-nitro anisidine Basic information
Product Name:2-Amino-4-nitro anisidine
Synonyms:1-Amino-2-methoxy-5-nitrobenzene;1-Methoxy-2-amino-4-nitrobenzene;2-methoxy-5-nitro-anilin;2-Methoxy-5-nitrobenzamine;2-methoxy-5-nitro-benzenamin;2-Methoxy-5-nitrobenzenamine;2-methoxy-5-nitro-Benzenamine;3-Amino-4-methoxynitrobenzene
CAS:99-59-2
MF:C7H8N2O3
MW:168.15
EINECS:202-770-5
Product Categories:Amines;Building Blocks;C7;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Intermediates of Dyes and Pigments
Mol File:99-59-2.mol
2-Amino-4-nitro anisidine Structure
2-Amino-4-nitro anisidine Chemical Properties
Melting point 117-119 °C(lit.)
Boiling point 337.07°C (rough estimate)
density 1.2068
vapor pressure 0.04Pa
refractive index 1.6010 (estimate)
Fp 119℃
solubility 382mg/L in organic solvents at 20 ℃
pka2.42±0.10(Predicted)
Colour Index 37130
Water Solubility Slightly soluble. <0.01 g/100 mL at 19.5 ºC
BRN 879620
Stability:Stable, but may be moisture sensitive. Incompatible with water, acids, strong oxidizing agents, acid chlorides, acid anhydrides, chloroformates, liquid anisidine.
LogP1.16 at 23℃
CAS DataBase Reference99-59-2(CAS DataBase Reference)
IARC3 (Vol. 27, Sup 7) 1987
NIST Chemistry ReferenceBenzenamine, 2-methoxy-5-nitro-(99-59-2)
EPA Substance Registry System2-Methoxy-5-nitroaniline (99-59-2)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 26-36-45-36/37
WGK Germany 2
RTECS BZ7175000
Hazard Note Irritant
TSCA Yes
HS Code 2922290090
Hazardous Substances Data99-59-2(Hazardous Substances Data)
MSDS Information
ProviderLanguage
Azoamine Scarlet K English
SigmaAldrich English
ACROS English
ALFA English
2-Amino-4-nitro anisidine Usage And Synthesis
Chemical Propertiesorange to brown powder
Chemical Properties5-Nitro-o-anisidine is an orange-red crystalline compound.
Uses2-Methoxy-5-nitroaniline was used in the synthesis of 5-(9-acridinylamino)-p-anisidines via reaction with 9-anilinoacridines. It was also used in the synthesis of disazo disperse dyes containing nitro and methoxy groups, used for the dyeing of polyester fibre.
DefinitionChEBI: 2-methoxy-5-nitroaniline is a member of 4-nitroanisoles and a substituted aniline.
General DescriptionOrange-red needles or orange powder.
Air & Water ReactionsInsoluble in water.
Reactivity Profile2-Amino-4-nitro anisidine is incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides and chloroformates .
Fire HazardFlash point data for 2-Amino-4-nitro anisidine are not available. 2-Amino-4-nitro anisidine is probably combustible.
Flammability and ExplosibilityNonflammable
Safety ProfileSuspected carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITRO COMPOUNDS OF AROMATIC HYDROCARBONS.
Potential Exposure5-Nitro-o-anisidine is a chemical intermediate in the production of C.I. Pigment red 23, which is used as a colorant for commodities, such as printing inks, interior latex paints; lacquers, rubber, plastics, floor coverings; paper coating; and textiles. It is also used with other C.I. coupling components to produce various hues of red, brown, yellow, and violet on cotton, silk, acetate and nylon.
ShippingUN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
IncompatibilitiesIncompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, acid chlorides; acid anhydrides; chloroformates.
Waste DisposalIncineration (982℃, 2.0 seconds minimum) with scrubbing for nitrogen oxides abatement.
Nitroaniline 4-Nitroanisole o-Anisidine 2-Methoxy-4-nitroaniline NITROGEN DIOXIDE anisidine Methoxy m-Anisidine 2-Methoxyethanol Amino resin,etherified Azoic Diazo Component 1 p-Anisidine 3-Nitroanisole 3,4-Difluoronitrobenzene 2-Amino-4-nitro anisidine 4-Nitroanthranilic acid Nitrobenzene 2-METHOXY-6-NITRO-PHENYLAMINE

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