ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Glycine derivative (RS)-3,5-DHPG

(RS)-3,5-DHPG

(RS)-3,5-DHPG Basic information
Product Name:(RS)-3,5-DHPG
Synonyms:DL-ALPHA-(3,5-DIHYDROXYPHENYL)GLYCINE;(RS)-3;2-amino-2-(3;5-dihydroxyphenyl)acetic acid;5-Dihydroxyphenylglycine;(RS)-3,5-DHPG;(RS)-3,5-DIHYDROXYPHENYLGLYCINE;TOC(RS)-3-5DHPG
CAS:19641-83-9
MF:C8H9NO4
MW:183.16
EINECS:
Product Categories:Glutamate receptor;Glutamate
Mol File:19641-83-9.mol
(RS)-3,5-DHPG Structure
(RS)-3,5-DHPG Chemical Properties
Melting point >181°C (Dec.)
storage temp. Desiccate at -20°C
solubility Acetonitrile (Slightly), Water (Slightly)
form Solid
color White to Off-White
Water Solubility Soluble to 10 mM in water
Stability:Hygroscopic
Safety Information
MSDS Information
(RS)-3,5-DHPG Usage And Synthesis
Uses(RS)-3,5-DHPG is a selective group I metabotropic glutamate receptor agonist which activates both mGluR1 and mGluR5. It has been shown that (RS)-3,5-DHPG can modulate Kir4.1 protein and mRNA in cultured rat retinal Müller cells.(RS)-3,5-DHPG acts as a potential target in treatment of parkinson''s disease.
Biological ActivitySelective group I metabotropic glutamate receptor agonist which activates both mGlu 1 and mGlu 5 . Also reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D.
(RS)-3,5-DHPG Preparation Products And Raw materials
Phenetole (RS)-3,5-DHPG (S)-3,5-DIHYDROXYPHENYLGLYCINE
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