N-BOC-4-Hydroxypiperidine

N-BOC-4-Hydroxypiperidine Basic information
Product Name:N-BOC-4-Hydroxypiperidine
Synonyms:1-Boc-4-piperidinol, tert-Butyl 4-hydroxy-1-piperidinecarboxylate;N-BOC-4-Hydroxypiperidine,97%;1-Boc-4-hydroxypiperidine ,98%;N-Boc-4hydropiperidine;1-(tert-Butoxycarbonyl)-4-hydroxypiperidine, tert-Butyl 4-hydroxypiperidine-1-carboxylate;N-Boc-4-hydroxy-1-piperidine;tert-butyl 4-hydroxypiperidin-1-carboxylate;1-Boc -4-hydroxypeiperidine
CAS:109384-19-2
MF:C10H19NO3
MW:201.26
EINECS:600-916-6
Product Categories:Heterocyclic Compounds;pharmacetical;Alcohols and Derivatives;Amines and Anilines;Pyrans, Piperidines &Piperazines;Piperidine;Piperidines;Pyrans, Piperidines & Piperazines
Mol File:109384-19-2.mol
N-BOC-4-Hydroxypiperidine Structure
N-BOC-4-Hydroxypiperidine Chemical Properties
Melting point 61-65 °C (lit.)
Boiling point 292.3±33.0 °C(Predicted)
density 1.107±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, Ethyl Acetate
pka14.80±0.20(Predicted)
form Powder
color White to cream
BRN 7202094
InChIInChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3
InChIKeyPWQLFIKTGRINFF-UHFFFAOYSA-N
SMILESN1(C(OC(C)(C)C)=O)CCC(O)CC1
CAS DataBase Reference109384-19-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
HazardClass IRRITANT
HS Code 29339900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
N-BOC-4-Hydroxypiperidine Usage And Synthesis
Chemical PropertiesWhite to cream powder
UsesN-Boc-4-hydroxypiperidine is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.
UsesUsed in a synthesis of N-heterocyclic alkyl ethers via the Mitsunobu reaction.
N-BOC-4-Hydroxypiperidine Preparation Products And Raw materials
Preparation Products4-Amino-1-Boc-piperidine-->1-Boc-4-methanesulfonyloxypiperidine-->Piperidine, 4-(1H-pyrazol-1-yl)- (9CI)-->N-BOC-3-HYDROXY-1,2,3,6-TETRAHYDROPYRIDINE-->4-PHENOXYPIPERIDINE-->SAR-407899-->MK8245-->4-(TOLUENE-4-SULFONYLOXY)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER -->4-Hydroxypiperidine hydrochloride-->4-Methoxypiperidine-->Triethylamine hydrochloride-->1N-BOC 4-(2'-METHYL-4'-NITROPHENOXY) PIPERIDINE-->1-Boc-4-(2-pyridyloxy)piperidine
4-Hydroxypiperidine Triacetonediamine HDH-PHARMA 24737 (2S,4R)-N-BOC-4-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID METHYL ESTER, 98% E.E., 95 tert-Butyl acetate Carbonyl iron powder 4-HYDROXY-PIPERIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 1-BOC-4-(3-CARBOXY-PHENOXY)-PIPERIDINE Diphenoxylate N-Carbobenzyloxyglycine tert-Butanol tert-Butyl peroxyacetate 4-Cyanophenol N-BOC-4-Hydroxypiperidine Haloperidol N-BOC-4-CARBOXYMETHOXY-PIPERIDINE DROPERIDOL (2R,4S)-N-BOC-4-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID METHYL ESTER

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