| | BARBITAL Basic information |
| | BARBITAL Chemical Properties |
| Melting point | 188-192°C | | Boiling point | 318.14°C (rough estimate) | | density | 1.2200 | | refractive index | 1.4200 (estimate) | | Fp | 11 °C | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 7.43(at 25℃) | | form | Solid | | color | Faintly bitter crystals from H2O; polymorphicforms; triagonal crystals, monoclinic prisms, monoclinicneedles, and triclinic cryst | | Water Solubility | 7.149g/L(25 ºC) | | Merck | 13,965 | | EPA Substance Registry System | 5,5-Diethylbarbituric acid (57-44-3) |
| | BARBITAL Usage And Synthesis |
| Description | Barbital is an analytical reference material that is categorized as a barbiturate. It acts as an agonist at GABAA receptors to induce central nervous system depression. Formulations containing barbital have been used as a sedative to treat insomnia and seizures in human and veterinary medicine. Barbital is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications. | | Description | Barbital (CRM) (Item No. 22854) is a certified reference material categorized as a barbiturate. Barbital is regulated as a Schedule IV compound in the United States. Barbital (CRM) (Item No. 22854) is provided as a DEA exempt preparation. This product is intended for research and forensic applications. | | Chemical Properties | White crystals or powder; bitter taste;
odorless. Stable in air. Soluble in
hot water, alcohol, ether, acetone, and ethyl acetate.
| | Uses | Prototype of the barbiturate hypnotics. | | Definition | ChEBI: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by two ethyl groups. Formerly used as a hypnotic (sleeping aid). | | Brand name | Dormileno;Escoderm;Hypnogene;Hypnox;Lidor;Megal;Plexonal;Somnytic tablets;Verinogen;Verodon;Veroletten;Verolitten;Veronigen. | | World Health Organization (WHO) | Barbital is a long-acting barbiturate which is controlled under
Schedule IV of the 1971 Convention on Psychotropic Substances. See WHO
comment for barbiturates.
(Reference: (UNCPS4) United Nations Convention on Psychotropic Substances (IV),
, , 1971) | | Safety Profile | Poison by ingestion, intravenous,intraperitoneal, and subcutaneous routes. Ingestion causespsychological effects in humans. Mutation data reported.When heated to decomposition it emits toxic fumes ofNOx. An hypnotic andsedative. | | Purification Methods | Crystallise barbital from water or EtOH and dry it in a vacuum over P2O5. [Beilstein 24 III/IV 1901.] |
| | BARBITAL Preparation Products And Raw materials |
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