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| | Furazabol Basic information |
| Product Name: | Furazabol | | Synonyms: | 17-alpha-methyl-5-alpha-androstano(2,3-c)(1,2,5)oxadiazol-17-beta-ol;17-beta-hydroxy-17-alpha-methyl-5-alpha-androstano(2,3-c)furazan;17-methyl-5-alpha-androstano(2,3-c)(1,2,5)oxadiazol-17-beta-ol;3-c)(1,2,5)oxadiazol-17-beta-ol,17-methyl-5-alpha-androstano(;androfurazanol;dh245;frazalon;miotolon | | CAS: | 1239-29-8 | | MF: | C20H30N2O2 | | MW: | 330.46 | | EINECS: | 214-983-0 | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Steroids | | Mol File: | 1239-29-8.mol |  |
| | Furazabol Chemical Properties |
| Melting point | 152-153° | | alpha | D +39.4° (c = 1.42 in CHCl3) | | Boiling point | 467.89°C (rough estimate) | | density | 1.0786 (rough estimate) | | refractive index | 1.6800 (estimate) | | solubility | Chloroform (Slightly), Methanol (Very Slightly), Pyridine (Very Slightly) | | pka | 15.14±0.60(Predicted) | | form | Solid | | color | Needles from methanol |
| Toxicity | LD50 in mice (g/kg): 2.330 orally; >4 s.c.; 0.494 i.p. (Kasahara, 1966) | | DEA Controlled Substances | CSCN: 4000
CSA SCH: Schedule III
NARC: No |
| | Furazabol Usage And Synthesis |
| Chemical Properties | White Solid | | Originator | Miotolon,Daiichi,Japan,1969 | | Uses | Furazabol is an anabolic steroid with hypocholesterolemic properties.
This is a controlled substance (anabolic steroid). | | Definition | ChEBI: Furazabol is a steroid. It derives from a hydride of an estrane. | | Manufacturing Process | A mixture of 2.0 grams of 2,3-dihydroxyimino-17α-methyl-5cα-androstan-17β-
ol, 5 ml of piperidine and 10 ml of ethylene glycol was heated at a
temperature between 180° and 190°C for 30 minutes. After the resulting
product was cooled, water was added thereto, and the separated product was
filtered, washed with water and dried. The product was dissolved in benzene
and passed through a column of alumina. The column was washed with ether,
and the eluted fractions were collected and condensed. Subsequently, the
residue was recrystallized from ether or aqueous methanol to produce 1.53
grams of 17β-hydroxy-17α-methyl-5α-androstano[2,3-c]furazan which has a
melting point of 152°C. | | Therapeutic Function | Anticholesteremic | | Safety Profile | Moderately toxic by ingestion andother routes. An experimental teratogen. Otherexperimental reproductive effects. When heated todecomposition it emits toxic fumes of NOx. |
| | Furazabol Preparation Products And Raw materials |
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