Hydroxybupropione

Hydroxybupropione Basic information
Product Name:Hydroxybupropione
Synonyms:HYDROXYBUPROPION;HYDROXYBUPROPIONE;1-(3-CHLOROOPHENYL)-2-[(2-HYDROXY-1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE;2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE;1-(3-Chloroophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone, 2-Hydroxy-2-(3chlorophenyl)-3,5,5-trimethylmorpholine;1-(3-Chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one;1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone;(±)-Hydroxybupropion solution
CAS:92264-81-8
MF:C13H18ClNO2
MW:255.74
EINECS:200-835-2
Product Categories:Intermediates & Fine Chemicals;Metabolites & Impurities;Bupropion;Pharmaceuticals
Mol File:92264-81-8.mol
Hydroxybupropione Structure
Hydroxybupropione Chemical Properties
Melting point 121-123°C
Boiling point 393.9±32.0 °C(Predicted)
density 1.150±0.06 g/cm3(Predicted)
Fp 2℃
storage temp. -20°C
solubility Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
pka15.43±0.10(Predicted)
form Solid
color White to Pale Yellow
Safety Information
Hazard Codes F,Xn
Risk Statements 11-20/21/22-36
Safety Statements 16-36/37
RIDADR UN 1648 3 / PGII
WGK Germany 2
HS Code 3822900000
MSDS Information
Hydroxybupropione Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesA metabolite of Bupropion, an antidepressant. The compound exists mainly as cyclic acetal (2-hydroxy-2-(3?chlorophenyl)-355-trimethylmorpholine). See US Pat. # 6342496
DefinitionChEBI: Hydroxybupropion is an aromatic ketone.
General Description(±)-Hydroxybupropion is a primary metabolite of bupropion. Bupropion is a pharmaceutical used as an antidepressant and a smoking cessation drug sold under the trade names Wellbutrin? and Zyban?. This Certified Spiking Solution? is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research.
Hydroxybupropione Preparation Products And Raw materials
Chlorodimethylphenylsilane HYDROXYAPATITE TYPE I Betaine 4-Hydroxybenzoic acid Hydroxy silicone oil Silicone oil (high temperature) 3,4'-DIAMINODIPHENYLMETHANE ALTRENOGEST DIMETHYLAMINOPYRIDINE, POLYMER-BOUND Bupropion hydrochloride Glycine Bupropion TRIS EDTA ACETATE BUFFER, 10X, DNASE, RNASE AND PROTEASE FREE, PH 8.3, FOR MOLECULAR BIOLOGY AMINO ACIDS CHLOROPHOSPHONAZO III N,N-Dimethyl-1,4-phenylenediamine Glycolic acid Camptothecin Series--10-hydroxycamptothecin

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