Trifluoromethyl iodide

Trifluoromethyl iodide Basic information
Uses Reactions
Product Name:Trifluoromethyl iodide
Synonyms:PERFLUOROMETHYL IODIDE;Freon13I1;freon13t1;iodotrifluoromethane(trifluoromethyliodide);Methane,trifluoroiodo-;monoiodotrifluoromethane;Trifluoromethyl iodide 99%;R13I1
CAS:2314-97-8
MF:CF3I
MW:195.91
EINECS:219-014-5
Product Categories:organofluorine compounds
Mol File:2314-97-8.mol
Trifluoromethyl iodide Structure
Trifluoromethyl iodide Chemical Properties
Melting point <−78 °C(lit.)
Boiling point −22.5 °C(lit.)
density 2.361
vapor pressure 540.5kPa at 25℃
refractive index 1.379
Fp -22.5°C
form Gas
Water Solubility Slightly soluble in water.
Sensitive Light Sensitive
BRN 1732740
Stability:Stable. Substances to be avoided include strong oxidizing agents. Avoid direct sunlight. Risk of explosion if heated under confinement. Flammable.
LogP2.41 at 22.85℃
CAS DataBase Reference2314-97-8(CAS DataBase Reference)
NIST Chemistry ReferenceMethane, trifluoroiodo-(2314-97-8)
EPA Substance Registry SystemTrifluoroiodomethane (2314-97-8)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 68
Safety Statements 36/37
RIDADR UN 1956 2.2
WGK Germany 1
RTECS PB6975000
27
Hazard Note Irritant
TSCA T
HazardClass 2.2
HS Code 2903780020
MSDS Information
ProviderLanguage
Iodotrifluoromethane English
SigmaAldrich English
ALFA English
Trifluoromethyl iodide Usage And Synthesis
Uses

Trifluoroiodomethane is used as a gaseous fire suppression flooding agent for in-flight aircraft and electronic equipment fires. It is also an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals. It is involved in the rhodium-catalyzed alfa-trifluoromethylation of alfa,beta-unsaturatedketones. It plays an important role as catalyst in the enantioselective alfa -trifluoromethylation of aldehydes through photoredox organocatalysis using a readily available iridium photocatalyst.

Reactions

Trifluoromethyl iodide reacts with [AuMeL] to give [AuMe2(CF3)L] and [AuIL](L = PMe3 or PMe2Ph), or [Au(CF3)L] and Mel (L = PPh3), or a mixture of these products (L = PMePh2). In some cases reaction of [AuMe(PMe3)] with CF3I gives [AuMe(CF3)I(PMe3)]. Evidence is presented that the reactions proceed, at least in part, by a free-radical chain mechanism.

Chemical Propertiescolourless gas
UsesReagent used in the rhodium-catalyzed α-trifluoromethylation of α,?-unsaturated ketones.
UsesTrifluoroiodomethane is used as a gaseous fire suppression flooding agent for in-flight aircraft and electronic equipment fires. It is also an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals. It is involved in the rhodium-catalyzed alfa-trifluoromethylation of alfa,beta-unsaturatedketones. It plays an important role as catalyst in the enantioselective alfa -trifluoromethylation of aldehydes through photoredox organocatalysis using a readily available iridium photocatalyst.
Synthesis Reference(s)Journal of the American Chemical Society, 107, p. 5014, 1985 DOI: 10.1021/ja00303a042
Flammability and ExplosibilityNotclassified
TRIBUTYLPROPYNYLSTANNANE TRIS(TRIMETHYLSILYL)SILANE Triphenylmethyl Chloride Chloroiodomethane Iodotrimethylsilane 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent DIFLUOROIODOMETHANE 3-(Trifluoromethyl)benzaldehyde Potassium iodide 2-(Trifluoromethyl)benzoic acid Trimethylsulfoxonium iodide Trifluoromethyl 4-Trifluoromethylphenol Diiodomethane Trifluoromethyl iodide Propidium iodide Iodomethane 2-Methylbenzotrifluoride

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