3-CARENE

3-CARENE Basic information
Product Name:3-CARENE
Synonyms:3-Carene, stabilized, 90%;δ-3-carene,3,7,7-trimethylbicyclohept-3-ene;CARENE, Delta-3-(SG);DELTA-CARENE;D-CARENE;CAREN-(3), ROH;3-CARVENE;3-CARENE WITH GC
CAS:13466-78-9
MF:C10H16
MW:136.23
EINECS:236-719-3
Product Categories:Bicyclic Monoterpenes;Biochemistry;Terpenes;Miscellaneous
Mol File:13466-78-9.mol
3-CARENE Structure
3-CARENE Chemical Properties
Melting point 25°C
Boiling point 168-169 °C/705 mmHg (lit.)
density 0.857 g/mL at 25 °C (lit.)
FEMA 3821 | DELTA-3-CARENE
refractive index n20/D 1.474(lit.)
Fp 115 °F
storage temp. 2-8°C
solubility Chloroform: Soluble; Methanol: Soluble
form Liquid
color Clear colorless to slightly yellow
Odorat 100.00 %. citrus terpenic herbal pine solvent resinous phenolic cypress medicinal woody
Odor Typecitrus
optical activity[α]20/D +15°, neat
Merck 1836
JECFA Number1342
Stability:Stable. Flammable. Incompatible with strong oxidizing agents.
LogP4.38
EPA Substance Registry System3-Carene (13466-78-9)
Safety Information
Hazard Codes Xi,N,Xn
Risk Statements 10-43-50/53-65-38-52/53
Safety Statements 16-26-36/37-60-61-62-37-24
RIDADR UN 2319 3/PG 3
WGK Germany 2
RTECS FH8400000
HazardClass 3.2
PackingGroup III
HS Code 29021990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
3-CARENE Usage And Synthesis
DescriptionHydroperoxides of Δ-3-carene are allergens contained in turpentine. Occupational exposure occurs in painters, varnishers, or in ceramic decoration. The percentage of Δ-3-Carene is higher in Indonesian turpentine than in Portugese.
Description(±)-3-Carene is a bicyclic monoterpene found in a variety of plants, including Cannabis. It decreases phagocytosis by rat alveolar macrophages when used at a concentration of 0.5 μM and decreases their viability at a concentration of 5 μM. (±)-3-Carene increases the expression and activity of alkaline phosphatase in mouse osteoblastic MC3T3-E1 subclone 4 cells, indicating induction of osteoblastic differentiation. It also induces calcium formation and increases the expression of osteopontin and type I collagen, which are related to osteoblast mineralization. (±)-3-Carene induces bronchoconstriction in isolated guinea pig lungs when exposed at an air concentration of 3,000 mg/m3.
Chemical PropertiesClear, colorless liquid. Stable to approx- imately 250C, resinifies with oxygen. Insoluble in water; miscible with organic solutions. Com- bustible.
Chemical Properties3-Carene has a sweet, pungent turpentine-like taste.
OccurrenceReported present in basil oil, bell pepper, bilberry, black currant berry juice and buds, fennel oil, grapefruit juice, kumquat peel oil, lemon peel oil, lime peel oil (cold pressed and distilled), lovage seed, mandarin peel oil, orange juice, orange peel oil, orange (bitter) peel oil, tangerine peel oil and other natural products.
UsesSolvent, intermediate. 3-Carene is a mutagenic compound that may be found in the fumes of heating freshly cut spruce and birch chips. 3-Carene is also found i many esential oils and it inhibits acetylcholinesterase activity.
DefinitionA terpene hydrocarbon with both a 6-member and 3-member ring.
PreparationExtracted from the pine tree oil.
Synthesis Reference(s)Tetrahedron Letters, 25, p. 5255, 1984 DOI: 10.1016/S0040-4039(01)81577-X
General DescriptionColorless liquid with a sweet, turpentine-like odor. Floats on water.
Reactivity Profile3-CARENE may react vigorously with strong oxidizing agents. May react exothermically with reducing agents to release hydrogen gas. In the presence of various catalysts (such as acids) or initiators, may undergo exothermic addition polymerization reactions. Will attack some forms of plastics [USCG, 1999].
Health HazardInhalation causes headache, confusion, respiratory distress. Ingestion irritates entire digestive system and may injure kidneys; if liquid enters lungs, it causes severe pneumonitis. Contact with eyes or skin causes irritation.
Contact allergensHydroperoxides of D-3-carene are allergens contained in turpentine. Occupational exposure occurs in painters, varnishers, or ceramic decoration. The percentage of D-3-carene is higher in Indonesian than in Portuguese turpentine.
3-CARENE Preparation Products And Raw materials
Preparation ProductsMETHYL(2R,3S)-2,2-DIMETHYL-3-(2-OXOPROPYL)-CYCLOPROPANEACETATE-->2,6,6-TRIMETHYL-2,4-CYCLOHEPTADIEN-1-ONE
4-METHYL-1-HEXENE 1,2-dimethylcyclopropane 4-METHYLOCTANE CIS-2-HEXENE 4-isopropyl-1-methylcyclohexene CIS-2-HEPTENE CIS-3-METHYL-2-PENTENE 1-METHYL-1-CYCLOHEPTENE 2-METHYL-1-HEXENE TRANS-2-HEPTENE 1,1-DIMETHYLCYCLOPROPANE 1,4-DIMETHYLCYCLOHEXENE CYCLOPROPANE,PROPYL- 2-METHYL-2-OCTENE 3-METHYLPENTANE 2-METHYL-1-BUTENE 4-Methyl-1-pentene 2-Methyl-1-pentene

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.