(1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol

(1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol Basic information
Product Name:(1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol
Synonyms:(1R,2R)-(-)-2-AMINO-1-PHENYL-1,3-PROPANEDIOL;(1R,2R)-2-AMINO-1-PHENYLPROPANE-1,3-DIOL;(2R,3R)-3-PHENYLSERINOL;(2R,3S)-PHENYLSERINOL;[R(R*,R*)]-2-amino-1-phenylpropane-1,3-diol;(1R,2S)-3-Phenylserinol;1,3-Propanediol, 2-amino-1-phenyl-, [R-(R*,R*)]-;(1R,2R)-1-Phenyl-2-amino-1,3-propanediol
CAS:46032-98-8
MF:C9H13NO2
MW:167.21
EINECS:256-250-8
Product Categories:Amino Alcohols (Chiral);Asymmetric Synthesis;Chiral Building Blocks;Synthetic Organic Chemistry;Amino Alcohols;Chiral Building Blocks;Organic Building Blocks
Mol File:46032-98-8.mol
(1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol Structure
(1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol Chemical Properties
Melting point 112-118 °C (lit.)
alpha -39 º (c=1, 1N HCl)
Boiling point 295.79°C (rough estimate)
density 1.1222 (rough estimate)
refractive index -26.5 ° (C=1, MeOH)
pka11.73±0.45(Predicted)
optical activity[α]23/D 37°, c = 1 in 1 M HCl
CAS DataBase Reference46032-98-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
RIDADR UN 3259 8/PG 3
WGK Germany 3
HS Code 29221985
MSDS Information
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(1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol English
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(1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol Usage And Synthesis
Chemical Propertiesyellow crystalline powder
Uses(1R,2R)-(?)-2-Amino-1-phenyl-1,3-propanediol can be used as a starting material to prepare:
  • Diaryl sulfides, used to synthesize sulfimides and N-tosylsulfimides, applicable as chiral ligands.
  • (S,S)-Reboxetine, a selective norepinephrine reuptake inhibitor (NRI).
  • L-2-Mercaptosuccinic acid, used in the synthesis of polyester with mercapto group.
(1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol Preparation Products And Raw materials
Chloramphenicol sodium succinate (+)-(4aR,10bR)-3,4,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol hydrochloride 1-Methoxy-2-propyl acetate Chloramphenicol D-THREO-[DICHLOROACETYL-1-14C]-CHLORAMPHENICOL 2-Phenyl-1,3-propanediol ALTRENOGEST DI(PROPYLENE GLYCOL) BUTYL ETHER CHLORAMPHENICOL, D-THREO-[1,2-14C] 6-Aminocaproic acid Glycine 3-Amino-1,2-propanediol 1,3-Propanediol PHENYL VALERATE DL-BETA-PHENYLSERINE THREO FORM (1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol CHLORAMPHENICOL-[RING-3,5-3H] Phenylacetic acid

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