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| | ACTINOMYCIN C Basic information |
| Product Name: | ACTINOMYCIN C | | Synonyms: | actinochrysin;hbf386;mixtureofdactinomycin(10%),actinomycinc2(45%),andactinomycinc3(45%);nsc-18268;sanamicia;sanamycin;ACTINOMYCIN C, STREPTOMYCES CHRYSOMALLUS;ACTINOMYCIN C | | CAS: | 8052-16-2 | | MF: | | | MW: | 0 | | EINECS: | 232-485-1 | | Product Categories: | Antibiotics | | Mol File: | Mol File | ![ACTINOMYCIN C Structure]() |
| | ACTINOMYCIN C Chemical Properties |
| Melting point | 252° | | alpha | D25 -325 to -349° (c = 0.25 in ethanol) | | Boiling point | 848.87°C (rough estimate) | | density | 1.0721 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | 2-8°C | | Merck | 13,1606 |
| | ACTINOMYCIN C Usage And Synthesis |
| Uses | Antineoplastic. | | Uses | Actinomycin C is an antibiotic produced by?Streptomyces chrysomallus that intercalates DNA. | | Purification Methods | (A commercial mixture of Actinomycin C1 5%, C2 30% and C3 65% is available). Actinomycin C1 (native) crystallises from EtOAc as red crystals, is soluble in CHCl3, *C6H6 and Me2CO, and has m 246-247o(dec), [] 20D -328o (0.22, MeOH) and max 443nm ( 25,000) and 240nm ( 34,000). Actinomycin C2 (native) crystallises as red needles from EtOAc and has m 244-246o(dec), [] D -325o (c 0.2, MeOH), max 443nm ( 25,300) and 240nm ( 33,400). Actinomycin C3 (native) recrystallises from cyclohexane, or *C6H6/MeOH/cyclohexane as red needles with m 238-241o (dec), [] D -321o (c 0.2, MeOH), max 443nm ( 25,000) and 240nm ( 33,300). [Brockman & Lackner, Chem Ber 101 1312 1968.] Itis light sensitive.[Beilstein 27 III/IV 9642.] |
| | ACTINOMYCIN C Preparation Products And Raw materials |
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