R-(-)-O-DesMethyl-Venlafaxine-d6;[2H6]-R- (-)-O-DesMethyl-Venlafaxine;R-(-)-O-Desmethyl Venlafaxine-d6Q: What is
R-(-)-O-Desmethyl Venlafaxine-d6 Q: What is the CAS Number of
R-(-)-O-Desmethyl Venlafaxine-d6 Q: What is the storage condition of
R-(-)-O-Desmethyl Venlafaxine-d6 Q: What are the applications of
R-(-)-O-Desmethyl Venlafaxine-d6
R-(-)-O-DesMethyl-Venlafaxine-d6 Chemical Properties
Safety Information
MSDS Information
R-(-)-O-DesMethyl-Venlafaxine-d6 Usage And Synthesis
Biological Activity
(R)-(-)-O-Desmethyl Venlafaxine D6 is the deuterium labeled (R)-(-)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].
References
[1]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28. [2]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.
R-(-)-O-DesMethyl-Venlafaxine-d6 Preparation Products And Raw materials
