ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid

2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid

2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid Basic information
Product Name:2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid
Synonyms:(S)-Duloxetine PhthalaMide;(S)-Duloxetine PhtalaMide;(S)-2-(methyl(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)carbamoyl)benzoic acid;2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid;Duloxetine-14;Duloxetine impurity 11/(S)-Duloxetine Phthalamide/(S)-2-(methyl(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)carbamoyl)benzoic acid;Duloxetine Phthalamide Impurityuruty;(S)-2-(methyl(3-(naphthalen-1-yloxy)
CAS:199191-67-8
MF:C26H23NO4S
MW:445.53
EINECS:
Product Categories:Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Mol File:199191-67-8.mol
2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid Structure
2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid Chemical Properties
Melting point >183°C (dec.)
Boiling point 695.1±55.0 °C(Predicted)
density 1.296±0.06 g/cm3(Predicted)
storage temp. -86°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
pka3.58±0.36(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid Usage And Synthesis
Uses(S)-Duloxetine Phthalamide is an impurity of (S)-Duloxetine present with enteric polymer hydroxypropylmethylcellulose phthalate (HPMCP) in dosage formulations.
2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid Preparation Products And Raw materials
(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL Duloxetine Related Compound F (10 mg) ((S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride) Duloxetine IMpurity A (R)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine Duloxetine impurity A Duloxetine impurity F (S)-3-(dimethylamino)-1-(thiophen-3-yl)propan-1-ol (S)-Duloxetine SuccinaMide Duloxetine iMpurity (alpha-hydroxy) 3-THIOPHENEPROPANAMINE, N,N-DIMETHYL-GAMMA-(1-NAPHTHALENYLOXY)-, ETHANEDIOATE(1:1) S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide DULOXETINE MALEATE (S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine rac Duloxetine 3-Thiophene IsoMer Oxalate 3-((2,2,2- trifluoroethyl)thio)aniline Duloxetine iMpurity (N-acetyl) Duloxetine N-DesMethyl Metabolite (RS)-4-(3-MethylaMino-1-thiophen-2-yl-propyl)-naphthalen-1-ol
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