1-(CHLOROACETYL)-L-PROLINE METHYL ESTER

1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Basic information
Product Name:1-(CHLOROACETYL)-L-PROLINE METHYL ESTER
Synonyms:1-(CHLOROACETYL)-L-PROLINE METHYL ESTER;Vildagliptin Impurity 13;Vildagliptin Impurity 10/Methyl (2S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylate;chloroacetyl L-proline methyl ester;vildagliptin Impurity U;Vildagliptin Impurity 78;L-Proline, 1-(2-chloroacetyl)-, methyl ester;(S)-methyl 1-(2-chloroacetyl)pyrrolidine-2-carboxylate
CAS:38074-72-5
MF:C8H12ClNO3
MW:205.64
EINECS:
Product Categories:
Mol File:38074-72-5.mol
1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Structure
1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Chemical Properties
Boiling point 316.2±37.0 °C(Predicted)
density 1.285±0.06 g/cm3(Predicted)
pka-3.02±0.40(Predicted)
Safety Information
MSDS Information
1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Usage And Synthesis
UsesN-Chloroacetyl-L-proline Methyl Ester is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.
1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Preparation Products And Raw materials
vildagliptin Impurity V Vildagliptin Related Compound F vildagliptin Impurity Q (S)-Pyrrolidine-2-carbonitrile hydrochloride 2-Pyrrolidinecarboxamide, 1-(trifluoroacetyl)-, (2S)- (9CI) Vildagliptin IMpurity 2 (Mixture of DiastereoMers) N-acetic acid-1-aMino-3-adaMantanol (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile VILDAGLIPTIN Vildagliptin Related Compound G vildagliptin Impurity R vildagliptin Impurity L vildagliptin Impurity T CHLOROAC-PRO-OH (S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide Vildagliptin Related Compound E vildagliptin Impurity O Vildagliptin Related Compound H

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