Benzaldehyde dimethyl acetal

Benzaldehyde dimethyl acetal Basic information
Product Name:Benzaldehyde dimethyl acetal
Synonyms:(dimethoxymethyl)-benzen;2-(1-Methoxyethoxy)benzaldehyde;Benzaldehyde diMethyl acetal, 98% 100ML;Benzaldehyde diMethyl acetal, 98% 250ML;Benzaldehde diMethyl acetal;Benzaldehyde diMethyl acetal, 97.5%;BENZALDEHYDE DIMETHYL ACETAL FOR SYNTHES;Intedanib Impurity 8
CAS:1125-88-8
MF:C9H12O2
MW:152.19
EINECS:214-413-0
Product Categories:Acetals/Ketals/Ortho Esters;Building Blocks;Aromatic Ethers;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Biochemistry;Reagents for Oligosaccharide Synthesis;bc0001
Mol File:1125-88-8.mol
Benzaldehyde dimethyl acetal Structure
Benzaldehyde dimethyl acetal Chemical Properties
Melting point 87-89 C
Boiling point 87-89 °C/18 mmHg (lit.)
density 1.014 g/mL at 25 °C (lit.)
FEMA 2128 | BENZALDEHYDE DIMETHYL ACETAL
refractive index n20/D 1.493(lit.)
Fp 157 °F
storage temp. Inert atmosphere,2-8°C
form Liquid
color Clear colorless
Odorat 100.00 %. green earthy rooty nutty vegetable spinach potato fungal almond winey
Odor Typegreen
Water Solubility decomposes
Sensitive Moisture Sensitive
JECFA Number837
BRN 2044501
InChIKeyHEVMDQBCAHEHDY-UHFFFAOYSA-N
LogP2.24
CAS DataBase Reference1125-88-8(CAS DataBase Reference)
NIST Chemistry ReferenceBenzaldehyde dimethyl acetal(1125-88-8)
EPA Substance Registry SystemBenzene, (dimethoxymethyl)- (1125-88-8)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 23-24/25
RTECS CU5774000
10-21
TSCA Yes
HazardClass IRRITANT
HS Code 29110000
ToxicityLD50 orally in Rabbit: 1220 mg/kg LD50 dermal Rabbit > 5000 mg/kg
MSDS Information
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Benzaldehyde dimethyl acetal Usage And Synthesis
Chemical PropertiesClear colorless liquid
Chemical PropertiesBenzaldehyde dimethyl acetal has a sweet, floral note; also reminiscent of almond
OccurrenceReported found in rhubarb and potato.
UsesBenzaldehyde dimethyl acetal used as an effective reagent for the construction of selenocarbonyl compounds.
UsesBenzaldehyde dimethyl acetal is suitable for use in the synthesis of 4,6-dihydroxy sugar, required for the total synthesis of Porphyromonas gingivalis 381 derived lipid A. It may be used in the preparation of 1-O-methyl-2,3-di-O-galloyl-β-D-glucose.
UsesBenzaldehyde dimethyl acetal may be used as an analytical reference standard for the quantification of the analyte in fresh and canned fish and Cinnamomum zeylanicum using gas-chromatography coupled to mass spectrometry (GC-MS).
DefinitionChEBI: (Dimethoxymethyl)benzene is a benzyl ether.
PreparationFrom benzaldehyde and methanol in the presence of calcium chloride and HCl; from benzaldehyde and tetramethylorthosilicate in the presence of anhydrous HCl in methanol
PreparationA mixture of ethylenediamine (1.2 g, 20 mmol), Ph3SbO (1.0 mmol), and P4S10 (2.0 mmol) was autoclaved under a pressure of CO2 (4.9 MPa). Imidazolidinone was isolated by column chromatography (silica gel; eluent: ethyl acetate/hexane, 1:1, v/v); yield 1.5 g (85%).
Taste threshold valuesTaste characteristics at 25 ppm: green, nutty, brown and sweet
General DescriptionThe abstraction of α-hydrogen atoms from benzaldehyde dimethyl acetal by active bromine at 80°C has been investigated.
Safety ProfileModerately toxic by ingestion. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Benzaldehyde dimethyl acetal Preparation Products And Raw materials
Preparation ProductsTRANS-BETA-NITROSTYRENE-->BENZYLIDENEMALONONITRILE-->BENZYL 2-ACETAMIDO-4,6-O-BENZYLIDENE-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE-->N-BENZYLDIETHYLAMINE-->BENZYL 2-ACETAMIDO-4,6-O-BENZYLIDENE-2-DEOXY-BETA-D-GLUCOPYRANOSIDE-->2-BORONOBENZALDEHYDE, PINACOL ESTER-->(E)-2-Nitroethenylbenzene-->2,4-dimethyl-3-phenyl-pentane-->(-)-DIMETHYL 2,3-O-BENZYLIDENE-L-TARTRATE-->BENZYL 4,6-O-BENZYLIDENE-ALPHA-D-MANNOPYRANOSIDE
4,7-DIHYDRO-2-PHENYL-1,3-DIOXEPIN 2,2-Dimethoxy-2-phenylacetophenone 3-Nitrobenzaldehydedimethylacetal (+)-2,3-O-BENZYLIDENE-D-THREITOL 4-N-HEXYL-BENZALDEHYDE DIETHYL ACETAL (+)-DIMETHYL 2,3-O-BENZYLIDENE-D-TARTRATE RARECHEM AL BP 0018 RARECHEM AL BP 0189 4-N-PROPYLBENZALDEHYDE DIETHYL ACETAL RARECHEM AL BP 0076 Benzaldehyde dimethyl acetal METHYL 4,6-O-BENZYLIDENE-ALPHA-D-GLUCOPYRANOSIDE 2-(3-BROMOPHENYL)-1,3-DIOXOLANE 4-(DIETHOXYMETHYL)BENZALDEHYDE 4-BUTYLBENZALDEHYDE DIETHYL ACETAL 3-(2-METHYL-1,3-DIOXOLAN-2-YL)ANILINE Fluorescamine Trimethyl orthobenzoate

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