3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID

3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID Basic information
Product Name:3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID
Synonyms:3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID;3'-Amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid;Eltrombopag Intermediate 2;EltroMbopag I;3-(3-aMino-2-hydroxyphenyl)benzoic acid;[1,1'-Biphenyl]-3-carboxylic acid, 3'-aMino-2'-hydroxy-;3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC;Eltrombopag olamine Intermediate 1
CAS:376592-93-7
MF:C13H11NO3
MW:229.23
EINECS:814-404-7
Product Categories:376592-93-7
Mol File:376592-93-7.mol
3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID Structure
3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID Chemical Properties
Melting point 222 °C(dec.)
Boiling point 474.8±45.0 °C(Predicted)
density 1.364
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka3.99±0.10(Predicted)
color Pale Yellow to Light Brown
InChIInChI=1S/C13H11NO3/c14-11-6-2-5-10(12(11)15)8-3-1-4-9(7-8)13(16)17/h1-7,15H,14H2,(H,16,17)
InChIKeyZXLYSSHNDUXXIN-UHFFFAOYSA-N
SMILESC1(C2=CC=CC(N)=C2O)=CC=CC(C(O)=O)=C1
Safety Information
HS Code 2922.50.5000
MSDS Information
3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID Usage And Synthesis
Uses3’-Amino-2’-Hydroxy-[1,1’]Biphenyl-3-carboxylic Acid is used in the synthesis of monoethanolamine salts. A hydrazine cleavage product from Eltrombopag (E508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia
3'-AMINO-BIPHENYL-3-CARBOXYLIC ACID Eltrombopag 3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID

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