|
| | Ginkgolide C Basic information |
| Product Name: | Ginkgolide C | | Synonyms: | GINKGOLIDE C;1,7-DIHYDROXY-GINKGOLIDE A;(1S,2R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-2,4,7b,11-tetrahydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione;Gingkolide C;bn52022;GinkgolideA,1,7-dihydroxy-, (1α,7β)-;CGinkgolid;Ginkgolide C, 98%, from Ginkgo biloba L. | | CAS: | 15291-76-6 | | MF: | C20H24O11 | | MW: | 440.4 | | EINECS: | | | Product Categories: | Pharmaceuticals;Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;Saponins;Intermediates & Fine Chemicals;standardized herbal extract | | Mol File: | 15291-76-6.mol |  |
| | Ginkgolide C Chemical Properties |
| Melting point | >3000 (dec) | | alpha | D24 -14.7° (c = 1 in ethanol) | | Boiling point | 813.8±65.0 °C(Predicted) | | density | 1.72±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly, Heated) | | pka | 10.88±0.70(Predicted) | | form | neat | | color | White to Off-White | | LogP | 1.719 (est) |
| | Ginkgolide C Usage And Synthesis |
| Description | Ginkgolide C is a flavone first extracted from G. biloba leaves with multiple reported biological functions. It has been identified as a selective platelet activating factor receptor antagonist (IC50 = 37.6 μM). Ginkgolide C has also been shown to increase lipolysis and to inhibit adipogenesis in adipocytes via the activated AMPK pathway. | | Chemical Properties | Crystalline Solid | | Uses | Reference compound for PAF receptors in biological systems. | | Uses | Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists. |
| | Ginkgolide C Preparation Products And Raw materials |
| Raw materials | 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-2,7b,11-trihydroxy-8-methyl-4-(phenylmethoxy)-, (1S,2R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)- | | Preparation Products | Ginkgolide B |
|
