ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Pyridine derivatives (5-Chloropyridin-3-yl)boronic acid

(5-Chloropyridin-3-yl)boronic acid

(5-Chloropyridin-3-yl)boronic acid Basic information
Product Name:(5-Chloropyridin-3-yl)boronic acid
Synonyms:5-CHLORO-3-PYRIDINEBORONIC ACID;5-CHLORO-3-PYRIDINYL BORONIC ACID;5-CHLOROPYRIDIN-3-YLBORONIC ACID;5-CHLOROPYRIDINE-3-BORONIC ACID;5-Chloropyridne-3-boronic acid;3-Chloropyridine-5-boronic acid;(3-Chloro-5-pyridyl)boronic acid;5-chloropyridin-3-yl-3-boronic acid
CAS:872041-85-5
MF:C5H5BClNO2
MW:157.36
EINECS:677-212-0
Product Categories:Heteroaryl Boronic Acids;Boronic Acids;Organoborons;Boronic Acids and Derivatives;Chemical Synthesis;Organometallic Reagents;blocks;BoronicAcids;Pyridines;Pyridine
Mol File:872041-85-5.mol
(5-Chloropyridin-3-yl)boronic acid Structure
(5-Chloropyridin-3-yl)boronic acid Chemical Properties
Melting point 255-260℃
Boiling point 335.3±52.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
storage temp. 2-8°C
form powder
pka5.91±0.10(Predicted)
color White
InChIKeyNJXYBTMCTZAUEE-UHFFFAOYSA-N
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
HS Code 2933399990
MSDS Information
(5-Chloropyridin-3-yl)boronic acid Usage And Synthesis
Uses5-Chloro-3-pyridineboronic acid can be used as an intermediate:
  • In the preparation of positron emission tomography (PET) radioligand [11C]MK-1064, which is applicable in the orexin-2 receptor imaging.
  • In the synthesis of orexin 2 receptor antagonist (2-SORA) MK-1064.
  • In the preparation of pyridyl-cycloalkyl derived microsomal prostaglandin E synthase-1 inhibitors.
  • In the synthesis of ATAD2 bromodomain inhibitors.

(5-Chloropyridin-3-yl)boronic acid Preparation Products And Raw materials
2,5-DICHLORO-3-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE 2-CHLORO-4-PYRIDINEBORONIC ACID 2-TERT-BUTYLOXYCARBONYLAMINO-5-CHLOROPYRIDINE-3-BORONIC ACID PINACOL ESTER 2-Chloro-5-pyridineboronic Acid (contains varying amounts of Anhydride),6-CHLORO-3-PYRIDINEBORONIC ACID,2-CHLORO-5-PYRIDINEBORONIC ACID 2,5-DICHLOROPYRIDINE-3-BORONIC ACID 5-CHLORO-2-FLUORO-4-PICOLINE-3-BORONIC ACID 4-CHLORO-3-PYRIDINEBORONIC ACID PINACOL ESTER 5-CHLORO-2-FLUOROPYRIDINE-3-BORONIC ACID PINACOL ESTER 5-Chloro-2-methoxypyridine-3-boronic acid 2,3-DICHLOROPYRIDINE-5-BORONIC ACID 3-CHLORO-2-METHOXYPYRIDINE-5-BORONIC ACID 5-Chloro-2-fluoropyridin-3-ylboronic acid 3-CHLORO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)PYRIDINE 2-CHLORO-3-PYRIDINEBORONIC ACID (5-Chloropyridin-3-yl)boronic acid 5-CHLORO-2-METHOXY-PYRIDINE-3-BORONIC ACID PINACOL ESTER 3-CHLORO-2-METHOXYPYRIDINE-5-BORONIC ACID PINACOL ESTER 2,3-DICHLOROPYRIDINE-5-BORONIC ACID PINACOL ESTER
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