ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Pyridine derivatives 4-Ethynylpyridine hydrochloride

4-Ethynylpyridine hydrochloride

4-Ethynylpyridine hydrochloride Basic information
Product Name:4-Ethynylpyridine hydrochloride
Synonyms:4-Ethynylpyridine HCl;4-Ethynylpyridine hychloride;4-Ethynylpyridine hydrochloride;4-pyridylacetylene HCl;REF DUPL: 4-pyridylacetylene HCl;4-Ethynylpyridinehychloride salt;4-EthynyL;pyridine hydrochL
CAS:352530-29-1
MF:C7H6ClN
MW:139.58
EINECS:627-680-7
Product Categories:Heterocycle-Pyridine series;C7 and C8;Heterocyclic Compounds;Heterocyclic Building Blocks;Pyridines
Mol File:352530-29-1.mol
4-Ethynylpyridine hydrochloride Structure
4-Ethynylpyridine hydrochloride Chemical Properties
Melting point 150 °C (dec.) (lit.)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
color Yellow to Brown to Dark green
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29333999
MSDS Information
4-Ethynylpyridine hydrochloride Usage And Synthesis
Uses4-Ethynylpyridine hydrochloride may be used in the preparation of the following 2-methyl-6-(phenylethynyl)pyridine (MPEP) analogs:
  • 1,4-bis(pyridin-4-ylethynyl)benzene
  • 4-((5,5-dimethyl-1,3,2-dioxaborinan-2-yl)ethynyl)pyridyl
  • 4-((3-iodophenyl)ethynyl)pyridine
  • 4-((4-iodophenyl)ethynyl)pyridine
  • 1,4-di(pyridine-4-yl)buta-1,3-diyne

It may also be used in the preparation of:
  • (rac)-2,8-bis(4-pyridylethynyl)-4,10-dimethyl-5,11-methano-6H,12H-dibenzo[b,f][1,5]diazocine, a Tr?ger′s base derived bis(pyridyl) ligand
  • (2RS,6RS)-2-(4-methoxyphenyl)-6-(2-(4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)ethyl)dihydro-2H-pyran-4(3H)-one, a substituted tetrahydropyrone
  • BINOL (1,1′-bi-2-naphthol)-based bis(4-pyridyl) ligands

General Description4-Ethynylpyridine hydrochloride acts as a ligand for the synthesis of various metallic complexes.
4-Ethynylpyridine hydrochloride Preparation Products And Raw materials
3-Picolyl chloride hydrochloride 4-Bromopyridine hydrochloride Pyridine hydrochloride 3-Pyridylacetic acid hydrochloride 1-BUTEN-3-YNE Trimethylsilylacetylene ETHYNYLMAGNESIUM BROMIDE Topotecan hydrochloride Methoxyammonium chloride 4-HYDRAZINOPYRIDINE HYDROCHLORIDE [MFCD00035353] 4-Ethynylpyridine 2-(Chloromethyl)pyridine hydrochloride 2-CHLORO-4-TRIMETHYLSILANYLETHYNYL-NICOTINIC ACID METHYL ESTER 4-Ethynylpyridine hydrochloride 4-Fluoropyridine hydrochloride 4-(Chloromethyl)pyridine hydrochloride 4-Chloropyridinium chloride
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